Publications by authors named "Gargi Ghoshal"

Treatment therapies used to manage osteoporosis are associated with severe side effects. So worldwide herbs are widely studied to develop alternative safe & effective treatments. Cissus quadrangularis (CQ) has a significant role in bone health and fracture healing.

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The probiotic beverage was developed using germinated and ungerminated pearl millet flour and green gram milk. The germinated and ungerminated pearl millet flour was added to green gram milk at different concentrations (0.5-2.

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In pulsed electric field (PEF) method sources of high voltage pulses are placed amid two electrodes in to fluid or paste type foods. Electricity is passed between two electrodes to sterilize the food. Almost all PEF technology entails the use of this technology in milk and milk product processing, eggs, poultry, juices and other liquid foods to prevent microorganisms.

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The present study described the formation of stable emulsion of flaxseed oil (0%, 0.25%, 0.50%, 0.

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The demand of proteins from both plant and animal origin is growing throughout the world. But the proteins obtained from animals have an environmental effect and are expensive in market. Sunflower seeds are particularly intriguing among plant proteins since they are widely available have high protein content, nutritive value and functionalities.

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This article aims to provide a comprehensive review of Cissus quadrangularis (CQ), which is a traditional medicinal herb and has a potential osteoprotective effect. CQ is a perennial climber of family Vitaceae that is commonly found in the hotter parts of India. It is most widely used in India for improving bone health and is well known as "hadjod.

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The objective of the present investigation was to identify and characterize the pigment produced by yeast strain (MTCC-1403) using food industry residues. Onion peel powder and Mung bean husks were explored as substrate for submerged fermentation at previously optimized conditions in 3-L bioreactor. The pigment extraction was followed by quantification and characterization in terms of UV-visible spectroscopy, Fourier transform infrared spectroscopy, high performance liquid chromatography and fluorescence spectroscopy.

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Composite films comprising modified corn starch and gelatin were developed using a solvent casting technique. The effect of varied content of citric acid and gelatin on the functional properties of the corn starch and composite films, respectively, was investigated. Modified corn starch films enriched with 5% citric acid presented excellent film properties like solubility, swelling index, water vapor permeability, and mechanical property as compared to other films.

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Carrot cellulose nano fibers (CNF) have been extracted from carrot pulp using acid hydrolysis process. The size of the CNF was in the range of 6.33-58.

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Bio-colorants are preferred over synthetic colors as bio-colorants not only impart characteristic color to the food also contain harmless bio-active antioxidant nutrients. The present study was undertaken to investigate the potential of agro-industrial waste (Onion peels, potato skin, mung bean husk and pea pods) for carotenoid production from After screening of appropriate carbon, nitrogen sources from agro-industrial waste, the fermentation conditions (pH, temperature, agitation) were optimized using Response Surface Methodology and optimum conditions were pH 6.1, temperature 25.

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In the current work, moth bean starch was separated from the moth bean seeds which were cultivated in the semi arid regions of Haryana and Rajasthan, India using alkali treatment technique and characterized. Isolated and purified moth bean starch comprised (12.89-20.

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Beta-carotene (BC), a red-colored pigment found in plants and animals, is one of the most extensively investigated carotenoids due to its provitamin-A, antioxidant, and anticancer properties. The anticancer activity of BC through oral administration is severely affected due to its low bioavailability and oxidative degradation. The present study aimed to formulate and characterize solid lipid nanoparticles (SLNs) of BC for enhanced bioavailability and therapeutic efficacy.

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The aim of this study was to develop fiber-enriched functional bread containing selected concentration of chitosan (0.1%, 0.5%, 1%, 1.

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The work entails a novel strategy of formulating the lycopene loaded whey protein isolate nanoparticles (LYC-WPI-NPs) solely using the rational blend of biomacromolecule without using equipment-intensive techniques. The LYC-WPI-NPs were fabricated as a substantial drug delivery platform, with maximum entrapment, spatial and controlled release manners, exceptional plasma concentration, and perspective for discrepancy delivery of therapeutics. Prepared nano-formulations were measured in ultra-fine size (100-350 nm) with sphere-shaped.

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Beta carotene (βC) loaded nanoparticles of zein (βC-NPs) were developed using modified phase separation technique. βC-NPs were prepared using different zein concentration and optimized formulation was selected on the basis of micromeritics properties and entrapment efficiency. Further, βC-NPs were evaluated for in vitro release, in vitro cell-survival, cellular localization and apoptosis induced in MCF-7 cells.

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Article Synopsis
  • * These carriers are effective because they bind to lectin receptors on cell surfaces, making them suitable for delivering various bioactive compounds.
  • * The review discusses advancements in galactosylated nanocarrier development, focusing on how they can actively target tumors and explaining the mechanisms of how these carriers interact with cell receptors.
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Aim: This work was intended to investigate the targeting potential of fructose-tethered lipid-polymeric hybrid nanoparticles (F-BC-MTX-LPHNPs) co-loaded with beta carotene (BC) and methotrexate (MTX) in breast cancer therapeutics and find out the possible protective role of BC on MTX-induced toxicity.

Materials & Methods: F-BC-MTX-LPHNPs were fabricated using self-assembled nano-precipitation technique. Fructose was conjugated on the surface of the particles.

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Article Synopsis
  • * The study developed microcapsules using casein and guar gum to enhance the stability and availability of β-carotene, achieving a successful ratio and resulting in high yield, small particle size, and effective encapsulation efficiency.
  • * The microcapsules demonstrated controlled release of β-carotene, maintained stability in digestive conditions, and showed promising antioxidant activity while minimizing degradation from light exposure.
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The present study investigates the anticancer efficacy of lycopene loaded lipidic nanostructured particles. With a homogenization-evaporation technique, lycopene loaded solid lipid nanoparticles (LYC-SLNs) were fabricated with different ratios of biocompatible viz. compritol ATO 888 and gelucire, and evaluated for their micromeretics properties, in vitro release, in vitro cytotoxicity, cellular uptake and apoptosis induced in MCF-7 cells.

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The current work entails a novel strategy of formulating the microparticles of lycopene solely using rational blends of biopolymers without using equipment-intensive techniques. The study is intended to enhance oral bioavailability of lycopene by controlling its release from micro-formulation and facilitating its absorption though lymphatic pathways. Considering the minimum particle size, maximum entrapment efficiency and loading capacity, the amounts of casein (i.

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Article Synopsis
  • The study investigates how pH, protein to polysaccharide ratio, polymer concentration, core material load, and ionic strength affect the complex coacervation process in casein and gum tragacanth mixtures.
  • Optimal coacervation was found at a pH of 4.35 with a Pr:Ps ratio of 2:1, leading to high coacervate yields (82.51%) and entrapment efficiency (79.36%) for β-carotene microcapsules, which had an average particle size of 159.71μm.
  • The research confirmed the effectiveness of the microcapsules in stabilizing β-carotene at different temperatures and highlights their potential for controlled release and protection of
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