[Prognosis of bleeding recurrence after endoscopic sclerotherapy of esophageal varices].

Objective: To improve prediction of recurrent bleeding after endoscopic sclerotherapy of esophageal varices.

Material And Methods: A prospective, observational, case-control study was performed. Immediate and long-term results of endoscopic sclerotherapy of esophageal varices were studied in 91 patients for the period from 2002 to 2016.

[The indices of lipid metabolism in the blood plasma of patients with chronic calculous cholecystitis].

Aim: The study of lipid fraction spectrum in plasma of patients with chronic calculous cholecystitis (CCC) before and after the operative intervention.

Materials And Methods: 28 female patients with CCC. Plasma lipids were measured before the operation, 1 and 5 days after it, at the discharge from hospital and in healthy donors.

[Choice of bile-diverting operations in neoplastic obstruction of the distal common bile duct].

Analysis of clinical material of 206 patients with tumor obstruction of the distal part of the common bile duct allowed the conclusion to be made on the expediency of applying endoscopic methods for jaundice correction as the first stage in preparation for the operation (122 patients) and also as the only and final operation (70 patients). Study of the immediate and late-term results of different variants of operations for bile diversion in obstruction of the distal choledochus (203 operations) showed the superiority of the Roux hepaticoejunoanastomosis in which recurrent jaundice due to obstruction of the cystic duct does not occur, as is encountered in creation of a cholecystoejunoanastomosis, and there are no conditions for the development of ascending cholangitis.

[The surgical treatment of patients with mechanical jaundice].

Bile-diverting operations in 386 patients with obstructive jaundice are analysed. It was caused by benign diseases in 202 patients (group 1) and by malignant tumors of the biliary tract and pancreas in 184 patients (group 2). Laparoscopic cholecystostomy was carried out in the first stage of treatment in each third patient.

[External and internal drainage in the surgery of inflammatory diseases of the gallbladder and extrahepatic bile ducts].

Of the 586 patients operated on for acute and chronic calculous cholecystitis, postcholecystectomy syndrome, 304 (51.8%) had external or internal drainage of the bile ducts been performed. External drainage was employed in 251, transduodenal papillosphincterotomy--in 87 patients, biliodigestive anastomosis was created in 52.

[Surgical interventions for obstruction of the extrahepatic bile ducts].

The results of surgical correction of obstruction of the extrahepatic bile ducts in 279 patients are presented. The operation of choice was choledocholithotomy, which was added by papillosphincterotomy and external drainage of the common bile duct in indications. In obstruction of bile ducts of the tumor genesis, the different biliodigestive anastomoses were created.

[Diagnostic and therapeutic laparoscopy in surgical practice].

The results of laparoscopy in 1,000 patients with various diseases are analysed. The indications for laparoscopy in different groups of patients are shown. Various laparoscopic operations were carried out on 789 patients.

[The diagnosis and treatment of diseases and injuries of the spleen].

Based on an analysis of treatment of 58 patients subjected to splenectomy, the authors recommend to perform autotransplantation of the spleen tissue if the spleen had to be resected.

[Pharmacokinetics of antipyrine in viral and alcoholic lesions of the liver].

Parameters of antipyrine pharmacokinetics have been studied in 82 patients with viral, alcoholic and combined liver affections and in 19 healthy subjects. All the patients exhibited changes showing a reduction of liver function responsible for drug metabolism. Disturbances of antipyrine pharmacokinetics were more pronounced in acute alcohol-aggravated hepatitis B than in hepatitis B without alcoholic aggravation.