Synthesis and properties of benzo [d,e]estra-1,3,5(10)-triene-3, 17 beta-diol 17-acetate.

A new pentacyclic analogue of estradiol, benzo[d,e]estradiol 17-acetate, has been prepared and investigated for its hormonal and antitumor activity. Unlike related testosterone derivatives, the new compound did not display any interesting property.

Prenatal diagnosis of placental tumor by ultrasound.

A case of placental chorioangioma is reported. To our knowledge, this is the first case diagnosed prenatally by ultrasonography, The complications of chorioangiomas include hydramnios, antepartum hemorrhage and premature labor, fetal demise, low birth weight and toxemia.