Training in occupational nursing in nursing students. Current situation in Spanish universities.

Objective: To analyse the implementation of subjects and knowledge related to Occupational Nursing (ON) in undergraduate nursing education.

Method: National multicentre study by means of an integrative review of the curricula of the Bachelor's Degree in Nursing compiled in 2023 from the Ministry of Universities. Duplicate curricula linked to the same university were eliminated.

Professional experience and case management as predictors of nursing good practices directed to the primary caregiver.

Aims: Identify nursing good practices related to caregivers in three basic health areas of the Valencian Community and analyze the impact of professional experience and the presence of a Nurse Case Manager on nursing good practices.

Method: Cross-sectional descriptive study. An anonymous, self-administered "ad hoc" questionnaire was used with 10 items: 8 individual and 2 institutional good practices.

1,2-Silyl Rearrangement in Gold Carbene Chemistry: Synthesis of Furyl-Decorated Tetrasubstituted Silylallene Derivatives.

The gold-catalyzed reaction of 2-en-4-ynones with alkynylsilanes provides fully substituted allene derivatives bearing furyl and silyl groups. This transformation would involve generation of a gold furyl carbene intermediate, which regioselectively undergoes a nucleophilic attack by the alkynylsilane at the electrophilic carbene carbon atom with the formation of a β-gold vinyl cation species. The subsequent release of the gold catalyst, accompanied by a 1,2-silyl shift, leads to the formation of tetrasubstituted allene products.

Incidence of confusional syndrome (delirium) in a Latin American university hospital.

Background: Little is known about the incidence of delirium and its subtypes in patients admitted to different departments of university hospitals in Latin America.

Objective: To determine the incidence of delirium and the frequency of its subtypes, as well as its associated factors, in patients admitted to different departments of a university hospital in Bogotá, Colombia.

Methods: A cohort of patients over 18 years of age admitted to the internal medicine (IM), geriatrics (GU), general surgery (GSU), orthopaedics (OU) and intensive care unit (ICU) services of a university hospital was followed up between January and June 2018.

Predictors of physical activity in older adults 65 years and older: findings in health survey of the Valencian Community.

Background: Physical activity is part of a healthy lifestyle in the older adult and is related to multiple variables that promote this behavior.

Objective: To identify the relationship and predictive power of sociodemographic variables, multimorbidity, severity index, risk of poor mental health, social support, affective support and confidential support with the time devoted to physical activity in the population over 65 years of age in the Valencian Community.

Methods: Cross-sectional descriptive analytical study of the data collected in the Health Survey of the Valencian Community on a total of 3,199 people over 65 years of age.

Dual polarization Fourier transform processor using geometric-phase lenses.

This work presents a novel optical system for polarization image processing using geometric-phase (Pancharatnam-Berry) lenses. Such lenses are half-wave plates where the orientation of the fast (slow) axis follows a quadratic relation with the radial coordinate, and they present the same focal length but opposite sign for left and right circular polarizations. Therefore, they split an input collimated beam in a converging beam and a diverging beam with opposite circular polarizations.

Leisure Programmes in Hospitalised People: A Systematic Review.

Nurses carry out holistic assessments of patients during hospital admission. This assessment includes the need for leisure and recreation. Different intervention programmes have been developed to meet this need.

Retrieving the phase of diffraction orders generated with tailored gratings.

A technique is performed to quantitatively evaluate the intensity and phase of the diffraction orders generated by tailored phase gratings displayed onto a liquid-crystal spatial light modulator (LC-SLM). The SLM displays the grating together with a lens to obtain the Fourier transform. The setup is converted into a polarization common-path interferometer by simply rotating a polarizer.

Looking beyond the Skin: Pathophysiology of Cardiovascular Comorbidity in Psoriasis and the Protective Role of Biologics.

Psoriasis is a chronic systemic inflammatory disease associated with a higher incidence of cardiovascular disease, especially in patients with moderate to severe psoriasis. It has been estimated that severe psoriasis confers a 25% increase in relative risk of cardiovascular disease, regardless of traditional risk factors. Although the underlying pathogenic mechanisms relating psoriasis to increased cardiovascular risk are not clear, atherosclerosis is emerging as a possible link between skin and vascular affection.

Factors Associated With Resilience During Long-Term Hemodialysis.

Background: Resilience has been associated with greater adherence to treatment, better outcomes, and improved quality of life (QOL) in people with chronic health conditions. This study aimed to identify sociodemographic, treatment accessibility-related, clinical, and psychological variables associated with resilience in patients with advanced chronic kidney disease (CKD) undergoing long-term hemodialysis (>6 months).

Methods: This was a multicenter, cross-sectional, and correlational study.

Nurses' Perception of Patient Safety Culture in a Referral Hospital: A Cross-Sectional Study.

Healthcare systems are becoming increasingly complex which is helping to promote a ‘culture of safety’ within them based on the best scientific evidence available. Indeed, creating a positive institutional culture of patient safety is reflected in health outcomes. The aim of this present study was to describe the perception of culture of safety by nurses in adult inpatient units in a tertiary hospital and to analyze adverse events reporting.

Health Inequities in LGBT People and Nursing Interventions to Reduce Them: A Systematic Review.

Background: Lesbian, gay, bisexual, and transgender (LGBT) people present poorer mental and physical health results compared to the heterosexual and cisgender population. There are barriers in the healthcare system that increase these health inequities.

Objective: To synthesise the available evidence on how nurses can intervene in reducing health inequities in LGBT people, identifying their specific health needs and describing their experiences and perceptions of the barriers they face in the healthcare system.

Socioeconomic status and access to multiple sclerosis treatment in Mexico.

Introduction: Multiple sclerosis (MS) is a chronic neurological autoimmune condition and the leading non-traumatic cause of neurological disability worldwide. Disease-modifying therapies (DMT) directly impact on the long-term prognosis of patients with MS preventing relapses and the associated disability progression. Here, we analyzed the impact of socioeconomic status (SES) on DMT access in Mexican patients.

Abacavir Increases Purinergic P2X7 Receptor Activation by ATP: Does a Pro-inflammatory Synergism Underlie Its Cardiovascular Toxicity?

The cardiovascular toxicity of Abacavir is related to its purinergic structure. Purinergic P2X7-receptors (P2X7R), characterized by activation by high concentrations of ATP and with high plasticity, seem implicated. We appraise the nature of the interplay between Abacavir and P2X7R in generating vascular inflammation.

Perceived Stress in Relation to Quality of Life and Resilience in Patients with Advanced Chronic Kidney Disease Undergoing Hemodialysis.

: Patients with chronic kidney disease undergo various stages of therapeutic adaptation which involve lifestyle modifications, physical changes, and adjustment to renal replacement therapy. This process produces adaptive stress. To identify how resilience, health- related quality of life, and sociodemographic, clinical, and hemodialysis routine-related variables are related to perceived stress in patients with chronic kidney disease receiving hemodialysis for more than six months.

Study of the Strengths and Weaknesses of Nursing Work Environments in Primary Care in Spain.

Background: Nursing work environments are defined as the characteristics of the workplace that promote or hinder the provision of professional care by nurses. Positive work environments lead to better health outcomes. Our study aims to identify the strengths and weaknesses of primary health care settings in Spain.

Predictive model of variables associated with health-related quality of life in patients with advanced chronic kidney disease receiving hemodialysis.

Purpose: Chronic kidney disease (CKD) affects over 10% of the global population. Health-related quality of life (HRQoL) has been identified as a reliable indicator for assessing the effectiveness of treatment in chronic patients, and resilience as a predictor of low levels of stress and higher QoL. The aim of this research is to identify the relationship between HRQoL, resilience, perceived stress, and the different sociodemographic and clinical routine variables of advanced chronic kidney disease (ACKD).

Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma.

Although immune checkpoint inhibitors (ICIs) have achieved unprecedented results in melanoma, the biological features of the durable responses initiated by these drugs remain unknown. Here we show the genetic and phenotypic changes induced by treatment with programmed cell death-1 (PD-1) blockade in a genetically engineered mouse model of melanoma driven by oncogenic BRAF. In this controlled system anti-PD-1 treatment yields responses in ~35% of the tumors, and prolongs survival in ~27% of the animals.

Patients with Moderate to Severe Psoriasis Associate with Higher Risk of Depression and Anxiety Symptoms: Results of a Multivariate Study of 300 Spanish Individuals with Psoriasis.

Psoriasis is a chronic skin disease associated with considerable physical and psychological comorbidities. Stress and emotional disturbances have been implicated in both triggering the onset and exacerbation of psoriasis. In order to determine the level of perceived stress and mood alterations in patients with psoriasis and their association with disease severity, 300 individuals completed diverse validated questionnaires assessing stress and psychological mood.

Publisher Correction: Ultraviolet radiation-induced DNA damage is prognostic for outcome in melanoma.

In the version of this article originally published, Extended Data Fig. 3 was incorrect. A duplicate of Extended Data Fig.