Publications by authors named "Gaoxing Qiao"
Risk factors for necrotizing enterocolitis in preterm infants: a Meta analysis.
Zhongguo Dang Dai Er Ke Za Zhi
August 2022
Objectives: To systematically evaluate the risk factors for necrotizing enterocolitis (NEC) in preterm infants.
Methods: PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure, and Wanfang Data were searched for case-control studies and cohort studies on the risk factors for NEC in preterm infants published up to December 2021. RevMan 5.
Purpose: This study aimed to evaluate the cost-effectiveness of a porcine-derived fibrin sealant (PFS) for treating cerebrospinal fluid (CSF) leaks in cranial surgery compared with sutures alone from the perspective of public hospital management in China.
Methods: A decision tree model of cranial surgery patients with intraoperative CSF leak was constructed in R 3.6.
Pegylated recombinant human granulocyte colony-stimulating factors (PEG-rhG-CSFs) are more commonly and widely used than recombinant human granulocyte colony-stimulating factors (rhG-CSFs) in preventing chemotherapy-induced neutropenia in patients with stage II-IV breast cancer. To reduce the financial burden on these patients, the corresponding medical insurance directory needs to be revised. To evaluate the cost-effectiveness of PEG-rhG-CSF versus rhG-CSF in patients with stage II-IV breast cancer in central China.
View Article and Find Full Text PDFBackground: Polypharmacy and related adverse consequences are common in the older adults, especially mortality, but the causality of this relationship remains unclear. This meta-analysis aimed to explore the relationship between polypharmacy and mortality in older adults.
Methods: We systematically searched Pubmed, Embase, and the Cochrane Library from inception until August 2021 to identify observational studies providing quantitative estimates on the association between polypharmacy(≥5drugs) and mortality in the elderly (≥65 years).
Article Synopsis
- Irisflorentin, a compound derived from the root of Belamcanda chinensis, shows anti-inflammatory and anti-tumor effects, and this study explores its metabolism in the lab using liver cells.
- Eleven metabolites of irisflorentin were identified, with one key metabolite (M10) being characterized as 6,7-dihydroxy-5,3',4',5'-tetramethoxy isoflavone.
- The metabolic processes of irisflorentin involve oxidation, demethylation, and glucuronidation, with major enzymes CYP 1A2 and 3A4 being crucial for the formation of M10, highlighting the potential for drug interactions.
Background: The influencing factors of diabetic kidney disease (DKD) in Chinese patients with type 2 diabetes mellitus (T2DM) were explored to develop and validate a DKD diagnostic tool based on nomogram approach for patients with T2DM.
Methods: A total of 2,163 in-hospital patients with diabetes diagnosed from March 2015 to March 2017 were enrolled. Specified logistic regression models were used to screen the factors and establish four different diagnostic tools based on nomogram according to the final included variables.