Targeting the Ophthalmic Diseases Using Extracellular Vesicles 'Exosomes': Current Insights on Their Clinical Approval and Present Trials.

Ophthalmic diseases encompass a diverse range of conditions, each necessitating tailored treatment strategies. In the realm of ophthalmic research and therapeutic interventions, various subtypes of exosomes are being explored for their regenerative, neuroprotective, and anti-inflammatory properties. Exosomes have garnered increasing attention as promising therapeutic vehicles due to their natural role in cell-to-cell communication and targeted delivery capabilities.

How protein topology controls allosteric regulations.

Allostery is an important regulatory mechanism of protein functions. Among allosteric proteins, certain protein structure types are more observed. However, how allosteric regulation depends on protein topology remains elusive.

Azobenzene-derived surfactants as phototriggered recyclable templates for the synthesis of ordered mesoporous silica nanospheres.

An azobenzene-derived surfactant behaves as a "smart" molecule. Not only is it used as the structure-directing agent to synthesize unique mesoporous silica nanospheres, but it can also be quickly released from the silica framework with UV light and subsequently recycled.