STAT1-mediated upregulation of lncRNA LINC00174 functions a ceRNA for miR-1910-3p to facilitate colorectal carcinoma progression through regulation of TAZ.

Several of the thousands of human long noncoding RNAs (lncRNAs) have been functionally characterized, yet their potential involvement in colorectal carcinoma (CRC) remains poorly understood. In present study, we aim to investigate the role of lncRNA LINC00174 in CRC carcinogenesis. We observed that increased expression of LINC00174 in CRC tissues and cells in comparison to their corresponding controls.

Decreased resting-state BOLD regional homogeneity and the intrinsic functional connectivity within dorsal striatum is associated with greater impulsivity in food-related decision-making and BMI change at 6-month follow up.

Increasing animal models as well as brain imaging studies among human suggest an association between substance-related impulsivity in decision-making and decreased function of dorsal striatum. However, the resting-state intrinsic functional organization of dorsal striatum underlying food-choice impulsivity remains unknown. To address this issue, we used resting-state functional MRI (rs-fMRI) to measure brain activity among adult females.

[Characteristics of soil moisture variation in different land use types in the hilly region of the Loess Plateau, China].

Soil water availability is a key factor restricting the ecological construction and sustainable land use in the loess hilly region. It is of great theoretical and practical significance to understand the soil moisture status of different land use types for the vegetation restoration and the effective utilization of land resources in this area. In this study, EC-5 soil moisture sensors were used to continuously monitor the soil moisture content in the 0-160 cm soil profile in the slope cropland, terraced fields, jujube orchard, and grassland during the growing season (from May to October) in the Yuanzegou catchment on the Loess Plateau, to investigate soil moisture dynamics in these four typical land use types.

Immunosuppressive effects of hypoxia-induced glioma exosomes through myeloid-derived suppressor cells via the miR-10a/Rora and miR-21/Pten Pathways.

While immunosuppressive environments mediated by myeloid-derived suppressor cells (MDSCs) have been well documented in glioma patients, the mechanisms of MDSC development and activation have not been clearly defined. Here, we elucidated a role for glioma-derived exosomes (GDEs) in potentiating an MDSC pathway. We isolated normoxia-stimulated and hypoxia-stimulated GDEs and studied their MDSC induction abilities in vivo and in vitro.

[Risk factors for delayed breastfeeding initiation based on decision tree model and logistic regression model].

To determine influential factors for delayed breastfeeding initiation.
 Methods: Using questionnaires to collect the data of 950 pregnant women and infants' feeding practices in Changsha, Hunan, logistic regression and decision tree model were used to determine influential factors for delayed breastfeeding initiation.
 Results: Mothers with timely breastfeeding initiation were 594 (62.

[Carbon balance of household production system in the transition zone from the Loess Plateau to the Qinghai-Tibet Plateau, China].

The transition zone from the Loess Plateau to the Qinghai-Tibet Plateau is one of the regions with most dramatic changes in agricultural production mode and most sensitive response to the carbon balance effect. This paper analyzed the carbon balance of the agriculture system along the altitude gradient in Tongwei, Weiyuan and Xiahe counties. The results showed that with the increase of altitude, the carbon emission, carbon fixation and carbon sink capacity of crops per unit area decreased accordingly, while the average carbon emission, carbon fixation and carbon source capacity of each household in livestock system increased.

[Spatial heterogeneity of soil moisture of mountain apple orchards with rainwater collection and infiltration (RWCI) system in the Loess Plateau, China].

Water scarcity is a critical factor influencing rain-fed agricultural production on the Loess Plateau, and the exploitation of rainwater is an effective avenue to alleviate water scarcity in this area. This study was conducted to investigate the spatial and temporal distribution of soil moisture in the 0-300 cm under a 21-year-old apple orchard with the rainwater collection and infiltration (RWCI) system by using a time domain reflectometer (TDR) probe on the Loess Plateau. The results showed that there was a low soil moisture zone in the 40-80 cm under the CK, and the RWCI system significantly increased soil moisture in this depth interval.

[Trophic niche partitioning of pelagic sharks in Central Eastern Pacific inferred from stable isotope analysis.].

As the apex predators of the open ocean ecosystems, pelagic sharks play important roles in stabilizing the marine food web through top-down control. Stable isotope analysis is a powerful tool to investigate the feeding ecology. The carbon and nitrogen isotope ratios can be used to trace food source and evaluate the trophic position of marine organisms.

The Relationship between Japanese Encephalitis and Environmental Factors in China Explored Using National Surveillance Data.

Japanese encephalitis (JE) is a serious public health issue. This study was undertaken to better understand the relationship between JE distribution and environmental factors in China. JE data from 2005 to 2010 were retrieved from National Notifiable Disease Report System.

Synthesis of novel laccase-biotitania biocatalysts for malachite green decolorization.

Biomimetic mineralization has emerged as a novel tool for generating excellent supports for enzyme stabilization. In this work, protamine was used to induce titanium (IV) bis(ammonium lactato) dihydroxide (Ti-BALDH) into titania nanoparticles. This biomimetic titanification process was adopted for laccase immobilization.

[Anterior corpectomy combined with intervertebral decompression and fusion for multilevel cervical spondylotic myelopathy].

Objective: To investigate the clinical outcomes of anterior corpectomy combined with anterior intervertebral decompression and fusion for multilevel cervical spondylotic myelopathy.

Methods: The clinical data of 28 patients with multilevel cervical spondylotic myelopathy who underwent surgery from October 2012 to June 2014 were retrospectively analyzed. There were 18 males and 10 females, aged from 45 to 77 years old with an average of (60.

Thermal Transition of Bimetallic Metal-Phenolic Networks to Biomass-Derived Hierarchically Porous Nanofibers.

The development and utilization of biomass resources could contribute to new materials for long-term sustainable energy storage and environmental applications, reduce environmental impacts, and meet the urgent need for green and sustainable development strategies. Herein, a bimetallic metal-phenolic network (MPN) was applied to incorporate different metallic element species into cattle skin and fabricate collagen-fiber-derived complex oxide nanofibers using natural polyphenols (Myrica tannins). Direct thermal transition of these biomass-MPN composites generates hierarchically porous nanofibers possessing micro- and mesoporous architectures along with a well-preserved macroscopic structure.

Discovery and characterization of conserved and novel microRNAs from blunt snout bream (Megalobrama amblycephala) by deep sequencing.

MicroRNAs (miRNAs) are short, single stranded RNA molecules with approximately 22 nts in length, which regulate the stability and translation of messenger RNAs in several organisms. To increase the repertoire of miRNAs characterized in M. amblycephala, we used the deep sequencing technology to sequence a small RNA library using pooled RNA sample isolated from the 4 different tissues of M.

REGγ Controls Hippo Signaling and Reciprocal NF-κB-YAP Regulation to Promote Colon Cancer.

Colorectal cancer is one of the most commonly diagnosed cancers closely associated with inflammation and hyperactive growth. We previously demonstrated a regulatory circuit between the proteasome activator REGγ and NF-kappaB (NF-κB) during colon inflammation, known to be important in the development of colitis-associated cancer as well as sporadic colorectal cancer. How the inflammatory microenvironment affects the Hippo pathway during colorectal cancer development is largely unknown.

The efficacy and safety of anti-PD-1/PD-L1 antibody therapy versus docetaxel for pretreated advanced NSCLC: a meta-analysis.

Antibodies against the immune checkpoint proteins PD-1 and PD-L1 are novel therapeutic drugs for the treatment of advanced non-small cell lung cancer (NSCLC). Many clinical trials involving these drugs achieved breakthroughs in patients previously treated for advanced NSCLC. However, the results of these clinical studies are not consistent.

[Comparison of clinical effects between anterior cervical Zero-incision fusion system and traditional nail plate system in the treatment of cervical spondylotic myelopathy].

Objective: To compare the short-term efficacy of anterior cervical discectomy and fusion(ACDF) with traditional nail plate system and Zero-profile device in the treatment of cervical spondylotic myelopathy(CSM).

Methods: The clinical data of 45 patients with CSM treated from July 2014 to August 2015 was retrospectively analyzed. There were 23 males and 22 females with an average age of 53.

Influences of Cesarean Delivery on Breastfeeding Practices and Duration: A Prospective Cohort Study.

Background: Mothers are encouraged to exclusively breastfeed for the first 6 months. However, cesarean delivery rates have increased worldwide, which may affect breastfeeding. Research aim: This study aimed to determine the potential effects of cesarean delivery on breastfeeding practices and breastfeeding duration.

Eye Movement Study on Attention Bias to Body Height Stimuli in Height Dissatisfied Males.

The present study investigated attention bias in response to height-related words among young men in China. 47 [26 high height dissatisfied (HHD) and 21 low height dissatisfied (LHD)] men performed a dot-probe task. Eye movement (EM) recordings showed that compared to LHD men, HHD men had an avoidance bias in response to height-related words, which was revealed by less frequent first fixations on both tall-related and short-related words, and showed significantly shorter first fixations on short-related words.

lncTCF7 is a negative prognostic factor, and knockdown of lncTCF7 inhibits migration, proliferation and tumorigenicity in glioma.

Long noncoding RNAs (lncRNAs) have been shown to play critical roles in cancer. lncTCF7 (gene symbol: WSPAR) has been reported to maintain stemness in hepatocellular carcinoma (HCC) stem cells. However, little is known about the role of lncTCF7 in glioma.

N-acetylcysteine (NAC) ameliorates Epstein-Barr virus latent membrane protein 1 induced chronic inflammation.

Chronic inflammation results when the immune system responds to trauma, injury or infection and the response is not resolved. It can lead to tissue damage and dysfunction and in some cases predispose to cancer. Some viruses (including Epstein-Barr virus (EBV)) can induce inflammation, which may persist even after the infection has been controlled or cleared.

Transcriptome analysis of the Chinese giant salamander () using RNA-sequencing.

The Chinese giant salamander () is an economically important animal on academic value. However, the genomic information of this species has been less studied. In our study, the transcripts of were obtained by RNA-seq to conduct a transcriptomic analysis.

Macrophage migration inhibitory factor promotes vasculogenic mimicry formation induced by hypoxia via CXCR4/AKT/EMT pathway in human glioblastoma cells.

Macrophage migration inhibitory factor (MIF) is over-expressed and secreted in various cancer cells in particular in response to hypoxia. Recent studies have shown that, under hypoxic conditions, glioblastoma (GBM) cells display the ability to drive blood-perfused vasculogenic mimicry (VM). The aim of this study was to investigate the underlying mechanism of MIF in the regulation of hypoxia-induced VM in GBM cells.

[Influential factors for postpartum depression based on the structural equation model in Kaifu District in Changsha].

To investigate the current status of the postpartum depression in Kaifu District in Changsha, and to explore the influential factors for postpartum depression.
 Methods: We selected the mothers, who had a delivery and met the inclusion criteria in Changsha during 2015, as the participants and established a prospective birth cohort study. The social demographic characteristics and health-related information for the mothers and their families were collected by using self-made questionnaire.

Iatrogenic Gastrointestinal Perforation Following Therapeutic Endoscopic Procedures: Management and Outcome.

The aim of this study was to analyze the location, the cause and treatment of iatrogenic gastrointestinal perforations following therapeutic endoscopic procedures. Perforation occurred in 12 patients out of 3,389, giving cases occurred intraoperatively or postoperatively. Among them, 6 cases were closed by titanium clipping and 1 case by purse string suture.

Adaptive recursive algorithm for optimal weighted suprathreshold stochastic resonance.

Suprathreshold stochastic resonance (SSR) is a distinct form of stochastic resonance, which occurs in multilevel parallel threshold arrays with no requirements on signal strength. In the generic SSR model, an optimal weighted decoding scheme shows its superiority in minimizing the mean square error (MSE). In this study, we extend the proposed optimal weighted decoding scheme to more general input characteristics by combining a Kalman filter and a least mean square (LMS) recursive algorithm, wherein the weighted coefficients can be adaptively adjusted so as to minimize the MSE without complete knowledge of input statistics.