Integrating carbon reduction and ecological resilience strategies in the silk road economic corridor.

The Silk Road Economic Belt has become a pivotal region for China's sustainable development, focusing on the balance between carbon emissions and ecological resilience. Understanding the coordination between these factors is crucial for advancing China's westward economic shift and optimizing urban and demographic structures. This study investigates the coupling and coordination dynamics between carbon emissions and ecological resilience across 15 key cities in the Silk Road Economic Belt, using data from 2008 to 2018.

Enhancing cold tolerance in tobacco through endophytic symbiosis with .

Tobacco, a warm-season crop originating from the Americas, is highly susceptible to cold stress. The utilization of symbiotic fungi as a means to bolster crops' resilience against abiotic stresses has been proven to be a potent strategy. In this study, we investigated the effect of endophytic fungus on the cold resistance of tobacco.

Cellular Nanoparticles Treat Coronavirus Infection .

Cellular nanoparticles (CNPs), which refer to nanoparticles coated with natural cell membranes, are promising for neutralizing pathological agents. Here, we use CNPs as a medical countermeasure against the infection of SARS-CoV-2 variants in an animal model. CNPs comprise polymeric cores coated with the plasma membranes of human macrophages.

Global research hotspots and trends of Buyang huanwu decoction: A visual analysis of the literature based on CiteSpace.

Background: Buyang huanwu decoction (BYHWD) has shown significant clinical efficacy in the treatment of several diseases, particularly stroke. However, bibliometric research has not been comprehensive.

Methods: BYHWD articles were collected from literature databases published from January 1, 1915, to March 31, 2024, including the China National Knowledge Infrastructure, Weipu, Wanfang, Pubmed, Scopus, and Web of Science Core Collection.

Determining normal and abnormal reference values for corrective osteotomy for congenital hand malformation: a study on the zone of provisional calcification and bone axis.

Purpose: This study aims to establish reference values for the normal bone axis in children to assess the effectiveness of corrective osteotomy procedures and guide the treatment of congenital hand malformations and post-operative axis deviations.

Methods: A retrospective study was carried out between January 1, 2022, and October 9, 2024. A total of 192 individuals were included.

Neurophysiological mechanisms underlying the influence of motivational intensity on emotion regulation choice.

Motivation is considered a crucial factor in determining emotion regulation choice (ER choice). Our previous study revealed that increased motivation led to a preference for distraction over reappraisal due to the narrowed attention, yet neural underpinnings supporting this phenomenon remain unclear. In this study, we used event-related potentials (ERPs) to investigate whether motivation influences ER choice by early attention processing (P2) or late resource engagement (LPP).

Predictable regulation of gut microbiome in immunotherapeutic efficacy of gastric cancer.

Immunotherapy has showcased remarkable progress in the management of gastric cancer (GC), prompting the need to proactively identify and classify patients suitable for immunotherapy. Here, 30 patients were enrolled and stratified into three groups (PR, partial response; SD, stable disease; PD, progressive disease) based on efficacy assessment. 16S rRNA sequencing were performed to analyze the gut microbiome signature of patients at three timepoints.

A novel label-free impedance biosensor for KRAS G12C mutations detection based on PET-RAFT and ROP synergistic signal amplification.

The KRAS G12C mutations, as crucial biomarkers, are closely associated with non-small cell lung cancer. Here, a novel label-free electrochemical biosensor with synergistic signal amplification of photocell energy transfer-reversible addition fragmentation chain transfer (PET-RAFT) and ring-opening polymerization (ROP) was developed for the first time for sensitive detection of KRAS G12C mutations. Specifically, hairpin DNA (hDNA), which act as biomolecular probe, was self-assembled on Au electrode surface by Au-S bond.

Study on the Correlation Between Renal Blood Perfusion and Kidney Injury in Different Weekly-Aged Type 2 Diabetic Mice.

Unlabelled: This study aims to explore the correlation between renal blood perfusion (RBP) and diabetic nephropathy (DN).

Methods: A total of 72 mice included db/db and db/m mice at the ages of 6, 14, and 22 weeks, forming six groups. RBP was assessed using Laser Speckle Contrast Imaging (LSCI).

Simulation Study on Diffusion and Local Structure of CH, CO, SO, and HO Mixtures into Double-Layers Graphene.

Graphene has been widely studied as an ideal material for the adsorption and separation. In this work, we used molecular dynamics simulations to investigate the evolution of diffusion and local structure of CH, CO, SO, and HO mixtures into double-layers graphene under seven different interlayer spacings and four different CO concentrations. The results showed that the adsorption of CH and CO molecules on the graphene surface weakened with increased interlayer spacing.

[Research progress of antiviral treatment for patients with chronic hepatitis B combined with metabolic fatty liver disease].

Chronic hepatitis B (CHB) mainly causes cirrhosis and hepatocellular carcinoma (HCC). Metabolic fatty liver disease (MAFLD) has become the most common chronic liver disease worldwide with the continuous changes in lifestyle and dietary patterns and the increase in the number of obese individuals. Consequently, the incidence rate of CHB combined with MAFLD is rapidly increasing.

Buyang Huanwu Decoction restores the balance of mitochondrial dynamics after cerebral ischemia-reperfusion through calcium overload reduction by the PKCε-Nampt-Sirt5 axis.

Ethnopharmacological Relevance: Stroke is a common condition that poses a significant threat to human health. Buyang Huanwu Decoction (BYHWD) is a traditional treatment used for stroke management. However, the exact mechanism by which BYHWD mitigates cerebral ischemia-reperfusion by regulating calcium overload and restoring mitochondrial function is not yet fully understood.

Physiological characteristics of blood pressure responses after combined exercise in elderly hypertensive patients: a systematic review and meta-analysis.

Objective: The aim of this investigation is to explore the efficacy of combined exercise in elderly patients with hypertension. Moreover, we aim to delve into the underlying mechanisms governing blood pressure regulation, with the objective of promoting the adoption of this exercise regimen among elderly hypertensive individuals.

Methods: In our study, we conducted a thorough search across multiple databases, including PubMed, Web of Science, Cochrane Library, Embase, and Scopus.

Automatic Obstacle Avoidance Trolley System Based on Two-Dimensional ReS/WSe Heterojunction Photodetector.

With the continuous advancement of intelligent vehicle technology, automatic obstacle avoidance (AOA) has become a crucial component of in-vehicle systems. This study introduces an AOA trolley system based on ReS/WSe heterojunction photodetectors. The device with type-II band alignment exhibits an impressive on/off current ratio of 7.

Comprehensive Insights into Arecoline Hydrobromide: Pharmacology, Toxicity, and Pharmacokinetics.

Arecoline hydrobromide (AH) is an active alkaloid found in betel nut. AH was first extensively employed for treatment of tapeworm infection in dogs in Australia. In the last 2 decades, AH has gained increasing attention due to its multiple and notable pharmacological activities in various diseases, including: acaricidal activity against cattle ticks; anticataract activity; therapeutic and alleviating effects against diabetes complications, including male reproductive damage and cataract; treatment of rheumatoid arthritis (RA); and protection against gastric ulcer.

A comprehensive review of microplastic aging: Laboratory simulations, physicochemical properties, adsorption mechanisms, and environmental impacts.

As a new type of ecological environment problem, microplastic pollution is a severe challenge faced by the world, and its threat and potential risk to the ecosystem have become a hot research spot in the current environmental field. Microplastics (MPs) in the natural environment will experience aging effect, aging will change the physical and chemical properties of MPs and affect the adsorption behavior. Recently reported characterization techniques of MPs and laboratory simulation of aging are reviewed.

The brain's first "traffic map" through Unified Structural and Functional Connectivity (USFC) modeling.

The brain's white matter connections are thought to provide the structural basis for its functional connections between distant brain regions but how our brain selects the best structural routes for functional communications remains poorly understood. In this study, we propose a Unified Structural and Functional Connectivity (USFC) model and use an "economical assumption" to create the brain's first "traffic map" reflecting how frequently each segment of the brain structural connection is used to achieve the global functional communication system. The resulting USFC map highlights regions in the subcortical, default-mode, and salience networks as the most heavily traversed nodes and a midline frontal-caudate-thalamus-posterior cingulate-visual cortex corridor as the backbone of the whole brain connectivity system.

Mechanism of foliar application of boron to alleviate cadmium toxicity in winter wheat (Triticum aestivum L.).

Our previous work shown that boron (B) can inhibit cadmium (Cd) absorption in winter wheat, while the mechanism is not well understood. In this study, the mechanism of foliage spray B on Cd uptake in Cd-contaminated farmland was characterized with three treatments: spraying distilled water (CK), spraying 0.3% B fertilizer (F0.