Publications by authors named "Gao S"

cv. Fubaiju (CMF) is regarded as one of the three most renowned varieties of white in China, and different extraction methods have significant effects on its composition and activities. Therefore, six extractions were used in this study to assess the effects on extracts.

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A Co-doped porous carbon was successfully fabricated by a facile carbonizing procedure using coal hydrogasification semi-coke (SC) as the carbon and cobalt nitrate as the magnetic precursors, respectively. The mass ratio of the precursors was changed to regulate the microwave absorption (MA) capabilities. The favorable MA capabilities are a result of a synergistic interaction be-tween the dielectric loss from the carbon framework, the magnetic loss from nano-sized Co particles, and multiple scattering from the residual pores.

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This study numerically investigated the dynamic process of residual saltwater contamination in subterranean reservoirs (aquifer upstream of subsurface physical barrier) for the first time. The results indicated that the groundwater level elevation resulting from subsurface physical barriers induced a small hydraulic gradient in the subterranean reservoir, with residual saltwater convection driven by the density contrast between saltwater and freshwater. This led to persistent inland intrusion of residual saltwater, causing a gradual expansion of the contamination area (i.

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Material surfaces maintaining a liquid super-repellent is crucial in fields such as anti-fouling, drag reduction, and heat transfer. Superhydrophobic surfaces provide an effective approach but suffer from phase change-induced wetting transitions, hindering their practical applications. In this work, Biphilic armored superhydrophobic surfaces (BASS) are designed by integrating hydrophilic interconnected surface frames with superhydrophobic nanostructures.

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The generation mechanism and regulation method of the radial higher-order orbital angular momentum (OAM) mode based on helically twisted elliptic fiber (HTEF) are investigated. This work aims to reveal the quantitative relation between the twisted rate (α) and the target radial higher-order OAM mode. From theoretical simulations, it is concluded that α is the key to regulating the radial higher-order OAM mode.

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  • * Music therapy has been shown to have therapeutic benefits for various neurological disorders, including epilepsy, but it can both help alleviate seizures and, in some cases, trigger them, complicating its effects.
  • * This review explores the influence of music on epilepsy by discussing its effects on the brain, its classification as either anti-convulsant or pro-convulsant, as well as the underlying mechanisms and future research directions regarding music's role in epilepsy management.
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Niosomes are key nanocarriers composed of bilayer vesicles formed by non-ionic surfactants and cholesterol, offering advantages such as high physicochemical stability, biodegradability, cost-effectiveness, and low toxicity. This review discusses their significant role in drug delivery, including applications in anticancer therapy and vaccine delivery. It also highlights the impact of non-ionic surfactants on niosome formation, drug delivery pathways, and protein corona formation-a relatively underexplored topic.

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Human biomechanical energy, with features of fluctuating amplitudes and low frequency, has been considered as a potential sustainable power source for wearable healthcare monitoring devices. Developing an effective energy harvester to ensure robust energy harvesting efficiency remains highly desired. Herein, we propose a wearable pendulum-rotor-separated triboelectric-electromagnetic hybrid generator (PTEHG).

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  • The study investigates the connection between obesity and non-alcoholic fatty liver disease (NAFLD) in Chinese youth, focusing on how specific adipokines and hepatokines serve as potential links between the two conditions.
  • Analysis was conducted on data from the Beijing Children and Adolescents Metabolic Syndrome (BCAMS) study, examining metabolic risks through ultrasound and plasma biomarker measurements to evaluate the obesity-NAFLD relationship.
  • Results showed strong associations between elevated levels of RBP4, FGF21, and leptin, along with decreased adiponectin, as predictors of NAFLD, indicating that dysregulated adipokines/hepatokines play a significant role in the development of obesity-related NAFLD in young individuals
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Tracheobronchomegaly (TBM) is a rare condition characterized by the dilatation of the trachea and bronchi due to severe atrophy of elastic fibers, accompanied by the thinning of the muscularis mucosae and the development of diverticula between cartilaginous rings. The etiology of this condition remains unclear. Tracheobronchopathia osteochondroplastica (TO) is another uncommon airway disease with an unknown etiology.

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  • A nomogram model was developed to predict acute lung injury (ALI) in sepsis patients using healthcare records from 193 hospitalized individuals.
  • Important predictive factors included the neutrophil/lymphocyte ratio (NLR), oxygenation index (PaO/FiO), tumor necrosis factor-α (TNF-α), and APACHE II scores, resulting in high accuracy and strong performance metrics.
  • The model's predictions aligned well with actual outcomes, indicating its potential as a useful clinical tool for identifying patients at higher risk for ALI.
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Information security awareness (ISA) has become a vital issue for organizations, as security breaches are usually attributed to human errors. ISP programs are effective ways to educate employees and enhance their information security knowledge. Gamification is a new concept in the area of ISA programs and it has been proven to be one of the most effective and proper ISA methods in both the private and public sectors.

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Background: Regulated cell death (RCD) has considerable impact on tumor progress and sensitivity of treatment. Lung adenocarcinoma (LUAD) show a high resistance for conventional radiotherapies and chemotherapies. Currently, regulation of cancer cell death has been emerging as a new promising therapeutic avenue for LUAD patients.

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  • * Findings reveal a strong connection between higher depressive symptoms and poorer cognitive performance, especially in episodic memory, alongside negative impacts on brain structure like reduced thalamic volume and white matter integrity.
  • * The study suggests that managing CVDs could be a potential strategy to prevent cognitive decline associated with depressive symptoms, emphasizing the importance of both mental and physical health in older adults.
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  • The review highlights advancements in non-nucleoside reverse transcriptase inhibitors (NNRTIs) aimed at improving HIV treatment by addressing issues like drug resistance and toxicity.
  • It emphasizes the role of computational chemistry and structure-based drug design in developing more effective and safer NNRTIs.
  • The article also discusses new chemical frameworks that show significant efficacy and how artificial intelligence is enhancing drug discovery to combat drug resistance in anti-HIV therapies.
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Background: The aim of this study was to elucidate the critical role of autophagy-related gene aggregation in gastric cancer tumor microenvironment cells and to investigate their major roles in cellular functions. In particular, the expression of these genes in tumor-associated fibroblast subtypes was scrutinized in an attempt to explain their cell-subpopulation-specific roles in cell-cell communication and regulation of cellular functions.

Methods: In this study, single-cell RNA sequencing data were first analyzed in multiple steps, including data preprocessing, cell clustering, and cell classification.

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  • Rice endosperm is crucial for seed germination and grain yield, yet the role of RNA editing during its development is not well understood.
  • The study investigates the RNA editome in rice endosperm, revealing that most editing occurs in mitochondrial genes and affects protein structure through C-to-U changes.
  • The researchers classify mitochondrial genes based on editing patterns and identify candidate proteins involved in the RNA editing process, enhancing our understanding of endosperm development.
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  • Kai-Xin-San (KXS) is an ancient herbal remedy traditionally used for treating amnesia, with modern studies showing its effectiveness against dementia and depression, though safety studies are limited.
  • Subacute and chronic toxicity studies were performed on rats to assess the drug's safety, examining symptoms, target organs, and recovery from potential toxic reactions.
  • Findings revealed gastrointestinal issues as the primary toxic effect, with a no-observed-adverse-effect-level (NOAEL) identified at 0.27 g/kg in the chronic study, indicating that safer doses exist.
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Despite heightened awareness of plastic contamination, a comprehensive understanding of the ecotoxicity of plastic leachates remains challenging due to discrepancies in previous findings and complexities in the effects of myriad factors. Herein, we proposed a multi-factor multi-effect plastic-leachate ecotoxicology meta-analysis approach (PLEM) to elucidate the ecotoxicity of plastic leachates on aquatic plants. To distinguish the leachate toxicity from the general effects of leachates and plastic particles, the previous studies on the effects of leachate stricto sensu (i.

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Cadmium (Cd) is currently one of the heavy metals with the highest environmental toxicity impact. Sodium thiosulfate (NaSO) is a commonly used heavy metal detoxification drug in clinical practice, however, it has not been used for Cd detoxification of Litopenaeus vannamei. The present study used exposure of L.

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  • The research focuses on enhancing the enzymatic activity of Zn-based single-atom nanozymes (SAzymes) for disease treatment by doping them with boron (B), which improves their biocompatibility.
  • By carbonizing a zinc-boron framework at various temperatures, a new form of B-doped Zn-based SAzymes (Zn-SAs@BNC) was created, leading to a modified electron configuration that boosts catalytic activity significantly.
  • The resulting Zn-SAs@BNC demonstrated impressive tumor-killing capabilities, underscoring its potential as an effective strategy for developing efficient anti-tumor therapies.
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  • - The study explores how soil minerals, particularly iron oxyhydroxides, affect the adsorption of hydrochar-derived dissolved organic matter (HDOM), showing that high molecular weight and oxidized compounds are preferentially absorbed while lower quality compounds stay in water.
  • - Using advanced mass spectrometry and toxicogenomics assays, it was found that original HDOM exposure primarily causes oxidative and DNA-related stresses in cells, but filtration through iron minerals reduces genotoxicity significantly.
  • - The selective absorption by iron minerals can alter the biotoxic impacts of HDOM, potentially affecting microbial community dynamics and ecological functions in both terrestrial and aquatic environments.
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Organoborons have recently received much attention, while a biocatalytic platform for the synthesis of chiral organoborons is limited only to cytochrome . In this study, we exploited the other heme protein, neuroglobin (Ngb), and engineered a quadruple mutant, A15C/H64G/V68F/F28M Ngb, by redesigning the heme active site using the structural information on A15C Ngb and molecular docking studies. The enzyme was shown to be efficient in catalyzing carbene transfer B-H insertion reactions between pyridine/quinoline boranes and benzyl 2-diazopropanoates and their derivatives (29 examples).

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Objective: Minimal change disease (MCD) is a common nephrotic syndrome that is usually steroid-sensitive and has high relapse rate. The aim of this study was to investigate the relationship between time to clinical remission and recurrence after the initial steroid therapy.

Methods: Among 305 adult patients diagnosed with MCD via light and electron microscopy, sensitive to steroids, and hospitalized for nephrotic syndrome in the Department of Nephrology of the Affiliated Hospital of Guangdong Medical University in China, 88 were included in this retrospective cohort study.

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