Liquid Processed Nano AsS/SWCNTs Composite Electrodes for High-Performance Li-Ion and Na-Ion Battery Anodes.

The liquid-phase exfoliation process has been successfully applied to nonlayered materials to produce quasi-2D nanoplatelets. A slight variation in bonding anisotropy in the starting material can result in the formation of 2D platelet-shaped particles with a relatively low aspect ratio. This advancement offers a promising strategy to create 2D materials from previously unexplored materials.

Skeletal Loading: Lean and Bone Mass Development in Young Elite Male Gymnasts, Swimmers, and Nonathletes Aged 6-24 Years.

Background: Exercise optimizes peak bone mass accrual, particularly if the loading is high magnitude and distributed in abnormal directions. Little is known about the influence of early intense training in sport during peak bone mass accrual, especially in boys.

Methods: Ninety-eight males aged 6-24 years (gymnasts, swimmers, and controls) completed the bone-specific physical activity questionnaire and a 7-day exercise diary.

Boron Nitride Nanosheet-Magnetic Nanoparticle Composites for Water Remediation Applications.

The combination of 0D nanoparticles with 2D nanomaterials has attracted a lot of attention over the last years due to the unique multimodal properties of resulting 0D-2D nanocomposites. In this work, we developed boron nitride nanosheets (BNNS) functionalized with manganese ferrite magnetic nanoparticles (MNPs). The functionalization process involved attachment of MNPs to exfoliated BNNS by refluxing the precursor materials in a polyol medium.

Boron Nitride Nanosheets Functionalized with FeO and CoFeO Magnetic Nanoparticles for Nanofiltration Applications.

Nanofiltration (NF) is one of the emerging technologies that is very promising for water purification among many other applications. 2D boron nitride (BN) based nanomaterials are excellent building blocks for NF membranes. In our work, BN nanosheets (BNNS) have been functionalized with magnetic nanoparticles (MNPs) to form BNNS-MNP nanocomposites.

High-dose olanzapine in treatment-resistant schizophrenia: a systematic review.

Background: Treatment-resistant schizophrenia (TRS) affects approximately 30% of people with schizophrenia. Clozapine is the gold standard treatment for TRS but is not always suitable, with a proportion of individuals intolerant of side effects or unable to engage in necessary blood monitoring. Given the profound impact TRS can have on those affected, alternative pharmacological approaches to care are needed.

Adeno-associated virus 2 infection in children with non-A-E hepatitis.

An outbreak of acute hepatitis of unknown aetiology in children was reported in Scotland in April 2022 and has now been identified in 35 countries. Several recent studies have suggested an association with human adenovirus with this outbreak, a virus not commonly associated with hepatitis. Here we report a detailed case-control investigation and find an association between adeno-associated virus 2 (AAV2) infection and host genetics in disease susceptibility.

Demonstrating the source of inherent instability in NiFe LDH-based OER electrocatalysts.

Nickel-iron layered double hydroxides are known to be one of the most highly active catalysts for the oxygen evolution reaction in alkaline conditions. The high electrocatalytic activity of the material however cannot be sustained within the active voltage window on timescales consistent with commercial requirements. The goal of this work is to identify and prove the source of inherent catalyst instability by tracking changes in the material during OER activity.

Understanding the effect of MXene in a TMO/MXene hybrid catalyst for the oxygen evolution reaction.

Very recently, it has been reported that mixed transition metal oxide (TMO)/MXene catalysts show improved performance over TMO only catalysts for the oxygen evolution reaction (OER). However, the reasoning behind this observation is unknown. In this work mixed Co(OH)/TiCT were prepared and characterized for the OER using ex situ and operando spectroscopy techniques in order to initiate the understanding of why mixed TMO/MXene materials show better performances compared to TMO only catalysts.

Isolation and Characterization of Phages for Phage Therapy.

is a clinically important pathogen causing a variety of antimicrobial resistant infections in both community and nosocomial settings, particularly pneumonia, urinary tract infection, and sepsis. Bacteriophage (phage) therapy is being considered a primary option for the treatment of drug-resistant infections of these types. We report the successful isolation and characterization of 30 novel, genetically diverse phages.

A randomised controlled trial of SAFMEDS to improve musculoskeletal radiology interpretation.

Introduction: This study examined the impact of a Say-All-Fast-Minute-Everyday-Shuffled (SAFMEDS) intervention on musculoskeletal radiology interpretation ability. It addressed two research questions: 1) what degree of performance improvement in musculoskeletal radiology interpretation does SAFMEDS engender beyond usual teaching? and; 2) does the degree of improvement differ for participants who achieve behavioural fluency and those who do not?

Materials And Methods: This study used a pragmatic randomised controlled trial design. Third-year medical students were randomised to either an intervention group (n = 22), who received SAFMEDS and usual teaching, or a control group (n = 20), who received usual teaching only.

Isolation and characterization of vibriophage vB_Vc_SrVc9: an effective agent in preventing Vibrio campbellii infections in brine shrimp nauplii (Artemia franciscana).

Aims: This study describes the physicochemical and genomic characterization of phage vB_Vc_SrVc9 and its potential for phage therapy application against a pathogenic Vibrio campbellii strain.

Methods And Results: A lytic phage vB_Vc_SrVc9 against V. campbellii was isolated from shrimp farm sediment, and characterized physicochemical and genomically.

Genome Sequence and Characterization of Coliphage vB_Eco_SLUR29.

Bacteriophages that infect are relatively easily isolated, with >600 coliphage genomes sequenced to date. Despite this there is still much to be discovered about the diversity of coliphage genomes. Within this study, we isolated a coliphage from cattle slurry collected from a farm in rural England.

Disorder Quenching of the Charge Density Wave in ZrTe_{3}.

The charge density wave (CDW) in ZrTe_{3} is quenched in samples with a small amount of Te isoelectronically substituted by Se. Using angle-resolved photoemission spectroscopy we observe subtle changes in the electronic band dispersions and Fermi surfaces upon Se substitution. The scattering rates are substantially increased, in particular for the large three-dimensional Fermi surface sheet.

Tandem Fluorescent Protein Timers for Noninvasive Relative Protein Lifetime Measurement in Plants.

Targeted protein degradation is an important and pervasive regulatory mechanism in plants, required for perception and response to the environment as well as developmental signaling. Despite the significance of this process, relatively few studies have assessed plant protein turnover in a quantitative fashion. Tandem fluorescent protein timers (tFTs) offer a powerful approach for the assessment of in vivo protein turnover in distinct subcellular compartments of single or multiple cells.

N-terminomics reveals control of Arabidopsis seed storage proteins and proteases by the Arg/N-end rule pathway.

The N-end rule pathway of targeted protein degradation is an important regulator of diverse processes in plants but detailed knowledge regarding its influence on the proteome is lacking. To investigate the impact of the Arg/N-end rule pathway on the proteome of etiolated seedlings, we used terminal amine isotopic labelling of substrates with tandem mass tags (TMT-TAILS) for relative quantification of N-terminal peptides in prt6, an Arabidopsis thaliana N-end rule mutant lacking the E3 ligase PROTEOLYSIS6 (PRT6). TMT-TAILS identified over 4000 unique N-terminal peptides representing c.

Bone Density and Cross-sectional Geometry of the Proximal Femur Are Bilaterally Elevated in Elite Cricket Fast Bowlers.

The skeleton of a cricket fast bowler is exposed to a unique combination of gravitational and torsional loading in the form of substantial ground reaction forces delivered through the front landing foot, and anterior-posterior shear forces mediated by regional muscle contractions across the lumbo-pelvic region. The objectives of this study were to compare the hip structural characteristics of elite fast bowlers with recreationally active age-matched controls, and to examine unilateral bone properties in fast bowlers. Dual-energy X-ray absorptiometry of the proximal femur was performed in 26 elite male fast bowlers and 26 normally active controls.

A device for the application of uniaxial strain to single crystal samples for use in synchrotron radiation experiments.

We present the design, construction, and testing of a straining device compatible with many different synchrotron radiation techniques, in a wide range of experimental environments (including low temperature, high field and ultra-high vacuum). The device has been tested by X-ray diffraction on single crystal samples of quasi-one-dimensional Cs2Mo6Se6 and K2Mo6Se6, in which microscopic strains up to a Δc/c = 0.12% ± 0.

Quantitative proteomics analysis of the Arg/N-end rule pathway of targeted degradation in Arabidopsis roots.

According to the Arg/N-end rule pathway, proteins with basic N-termini are targeted for degradation by the Arabidopsis thaliana E3 ligase, PROTEOLYSIS6 (PRT6). Proteins can also become PRT6 substrates following post-translational arginylation by arginyltransferases ATE1 and 2. Here, we undertook a quantitative proteomics study of Arg/N-end rule mutants, ate1/2 and prt6, to investigate the impact of this pathway on the root proteome.

Insights into relationships between body mass, composition and bone: findings in elite rugby players.

Recent reports indicate that bone strength is not proportional to body weight in obese populations. Elite rugby players have a similar body mass index (BMI) to obese individuals but differ markedly with low body fat, high lean mass, and frequent skeletal exposure to loading through weight-bearing exercise. The purpose of this study was to determine relationships between body weight, composition, and bone strength in male rugby players characterized by high BMI and high lean mass.