Extended Spectrum Beta Lactamase (ESBL), bla,bla and bla, Resistance Genes in Community and Healthcare Associated Gram Negative Bacteria from Osun State, Nigeria.

Background: Extended Spectrum Beta Lactamase (ESBL) production in gram negative bacteria confers multiple antibiotic resistance, adversely affecting antimicrobial therapy in infected individuals. ESBLs result from mutations in β-lactamases encoded mainly by the bla,bla and bla genes. The prevalence of ESBL producing bacteria has been on the increase globally, especially its upsurge among isolates from community-acquired infections has been observed.