A new type of biomaterial called Haptide-coated Collagen was developed, using a specific peptide from fibrinogen that enhances cell adhesion.
The optimal concentration of Haptide for enhancing cell attachment was found to be 5-10 mg Haptide/g collagen, leading to a more stable material that degrades slower than untreated collagen.
In animal studies, Haptized collagen attracted more fibroblasts and demonstrated improved integration with tissue, suggesting promising uses in medical fields like tissue regeneration and wound healing.