Calcium Carbonate from Anadara granosa Shells Stimulates FGF2, TGF-β1, and Collagen Type 1 Expression in Rat Dental Pulp.

Objectives:  Calcium carbonate (CaCO), a major inorganic component in bones and teeth, offers potential protection against demineralization. This study investigates the effect of CaCO from shells on the expression of fibroblast growth factor 2 (FGF2), transforming growth factor-β1 (TGF-β1), and collagen type 1 in the rat dental pulp.

Materials And Methods:  The first maxillary molars of were perforated and subsequently pulp capped with CaCO extracted from shells.

CaCO from shell as reparative dentin inducer in odontoblast pulp cells: In-vivo study.

Introduction: (blood clam) shell contained 98.7% of calcium carbonate (CaCO). This material has bio-properties that able to induced the dentin regeneration.