Nanosecond Laser Cataract Surgery in LOCS III Grade 4 and 5: A Case Series.

Purpose: A major obstacle to the widespread implementation of nanosecond laser cataract removal has been its limited efficacy in cases when the cataract is harder than Lens Opacities Classification System III (LOCS III ) grade 3. The latest technological modifications seem to have overcome this obstacle.

Design: A case series.

Visual acuity change after intravitreal bevacizumab for exudative age-related macular degeneration in relation to subfoveal membrane type.

Purpose: To examine an association between the subfoveal neovascular membrane type and visual acuity change after intravitreal bevacizumab injection for exudative age-related macular degeneration (AMD).

Methods: We carried out a clinical, retrospective, interventional case-series study including 66 consecutive patients (67 eyes) with exudative AMD who received an intravitreal injection of 1.5 mg bevacizumab.

Triamcinolone acetonide-induced ocular hypertension.

Purpose: The aim of this study is to report on the clinical course of a patient showing markedly increased intraocular pressure (IOP) caused by intravitreal triamcinolone acetonide.

Methods: A 33-year-old patient received an intravitreal injection of approximately 20 mg of triamcinolone acetonide (TA) as treatment of otherwise therapy-resistant uveitis. She experienced an IOP rise to values over 40 mmHg for a period for more than 3 months, despite maximal antiglaucomatous medical therapy.

Effect of uncomplicated phacoemulsification on the central retina in diabetic and non-diabetic subjects.

Background: The purpose of this study was to evaluate the subclinical influence of uncomplicated cataract surgery on foveal thickness and volume in the early postoperative period.

Methods: In a prospective study, 108 eyes were assessed by optical coherence tomography preoperatively and 1 day, 1 week and 4 weeks after uncomplicated small incisional phacoemulsification with endocapsular intraocular lens (IOL) implantation under topical anesthesia. The study included 24 eyes of diabetic patients.

Intravitreal triamcinolone acetonide for diabetic macular edema: a prospective, randomized study.

Purpose: The aim of this study was to examine the visual outcome of patients receiving an intravitreal injection of triamcinolone acetonide (TA) as treatment of diffuse diabetic macular edema (DDME).

Methods: This prospective, placebo-controlled, randomized, clinical interventional study included 40 eyes (38 patients) with DDME, with 28 (70%) eyes randomized to treatment and 12 (30%) eyes randomized to receive a placebo injection. Thirty-six (36) (90%) eyes completed the 3-month study visit, and 32 (80%) eyes completed the 6-month study visit.

Limbal stem cell deficiency after subconjunctival mitomycin C injection for trabeculectomy.

Purpose: To report on severe limbus cell insufficiency after trabeculectomy with subconjunctival injection of mitomycin C.

Design: Interventional small case-series.

Methods: Seven consecutive Caucasian patients (seven eyes) underwent penetrating trabeculectomy that included subconjunctival injection of 0.

Retrobulbar catheter anesthesia as a routine technique for retinal and vitreoretinal surgery.

To ascertain the safety of the retrobulbar catheter technique for intraoperative local anesthesia and titratable postoperative analgesia, 1,423 consecutive retinal or vitreoretinal surgeries were reviewed. Using a commercially available retrobulbar needle, a 28-gauge flexible catheter was introduced into the retrobulbar space before surgery and was removed the next morning. When pain occurred, a local anesthetic was re-injected intraoperatively or postoperatively through the catheter.

Intravitreal triamcinolone acetonide for treatment of acute nonarteritic anterior ischemic optic neuropathy.

Purpose: To report on the use of intravitreal triamcinolone acetonide as treatment for nonarteritic anterior ischemic optic neuropathy (NAION).

Methods: The interventional clinical case series included three patients with acute NAION who received an intravitreal injection of about 20 mg triamcinolone acetonide.

Results: At the end of follow-up at 3 months, 3.

Repeated intravitreal high-dosage injections of triamcinolone acetonide for diffuse diabetic macular edema.

Objective: To report the results of repeated intravitreal injections of triamcinolone acetonide for treatment of diffuse diabetic macular edema.

Design: Retrospective interventional comparative study.

Participants: The investigation included a study group (the responders) of 19 patients (22 eyes) with diffuse diabetic macular edema, who showed an improvement in visual acuity after an intravitreal injection of approximately 20 mg triamcinolone acetonide, and who received a second intravitreal injection 10.

Vitreous prolapse and IOL dislocation during intravitreal injection of triamcinolone acetonide.

Background: To report on procedure-related anterior segment complications during intravitreal injections.

Methods: In a prospective interventional case series, 614 eyes received a total of 723 intravitreal injections of about 20 mg triamcinolone acetonide (in 0.2 ml) after paracentesis and aqueous humor drainage for various indications.

Topical anesthesia for transpupillary silicone oil removal combined with cataract surgery.

Purpose: To assess safety of topical anesthesia for transpupillary silicone oil removal in combination with cataract surgery.

Setting: Department of Ophthalmology Mannheim, University of Heidelberg, Mannheim, Germany.

Methods: The clinical interventional study included 37 consecutive patients having transpupillary silicone oil removal combined with cataract surgery.

Phototoxic maculopathy after secondary intraocular lens implantation.

We report phototoxic maculopathy in 2 aphakic patients after secondary, scleral-sutured intraocular lens implantation. This rare complication may have been triggered by drugs that increased the photosensitivity of the tissue. Careful preoperative assessment is necessary to question the receipts of photosensitizing drugs and identify diseases that predispose patients to phototoxic injuries.

[Grid laser photocoagulation in diffuse diabetic macular edema].

Background: To evaluate the clinical outcome of macular grid laser photocoagulation in the treatment of diffuse diabetic macular oedema.

Patients And Method: The retrospective study included 30 consecutive patients (41 eyes) who were treated by macular argon green grid laser photocoagulation for diffuse diabetic macular oedema. Follow-up time was 31.

Topical versus peribulbar anaesthesia for cataract surgery.

Background: To assess and compare the efficacy and safety of topical versus peribulbar anaesthesia in patients undergoing routine cataract surgery.

Methods: The unicentre, prospective, randomized, clinical interventional trial included 140 consecutive patients undergoing routine cataract surgery performed by one of two surgeons. The patients were randomly distributed to either peribulbar anaesthesia or topical anaesthesia.

Topical anesthesia for penetrating trabeculectomy.

Purpose: To evaluate the efficacy and clinical practicability of topical anesthesia in comparison with retrobulbar anesthesia for penetrating trabeculectomy.

Methods: The prospective single-surgeon clinical interventional trial included 20 consecutive patients, who were randomly distributed into a topical anesthesia group ( n=10) and a retrobulbar anesthesia group ( n=10). In the topical anesthesia group, patients received preoperatively oxybuprocaine 0.