Publications by authors named "Gangfeng Zhao"
Phytomedicine
December 2024
Article Synopsis
- Diabetic cardiomyopathy (DCM) is a type of heart dysfunction that occurs without coronary artery disease and can lead to heart failure, with limited treatments available.
- Polydatin (PD), derived from traditional herbs, shows promise in improving the condition, although its exact cardioprotective mechanisms, particularly regarding a protein called Cav1, are not fully understood.
- The study found that PD significantly improved heart function in diabetic mice, but its benefits were lost when Cav1 was absent, suggesting that Cav1 plays a crucial role in PD's ability to protect the heart from diabetes-related damage.
