Publications by authors named "Gang-Yan Zhu"
Objective: Coronavirus disease 2019 (COVID-19) has raised concern around the world as an epidemic or pandemic. As data on COVID-19 has grown, it has become clear that older adults have a disproportionately high rate of death from COVID-19. This study describes the early clinical characteristics of COVID-19 in patients with more than 80 years of age.
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- The study aimed to evaluate malnutrition risk among elderly inpatients in China using two screening tools: Nutritional Risk Screening 2002 (NRS2002) and Mini-Nutritional Assessment (MNA).
- Conducted in eight medical centers, the study involved 425 patients aged 70 and older and found a high prevalence of malnutrition, with 40.9% identified by NRS2002 and 58.6% by MNA.
- Both screening tools showed significant correlations with age, BMI, and laboratory parameters, demonstrating that they are effective for assessing malnutrition risk in this population, with NRS2002 showing moderate agreement with MNA.
Multidrug resistance protein 4 (MRP4) is capable of transporting acyclic nucleotide phosphonates, but little is known about its role in lamivudine (LAM) and entecavir (ETV) transport. In the present study, the involvement of MRP4 in the transport of LAM and ETV was investigated through in vitro experiments. The cytotoxicity of three antiviral drugs and their activities against HBV as characterized in HepG2.
View Article and Find Full Text PDF[The prevalence of J wave in apparently healthy subjects in Hubei province of China].
Zhonghua Xin Xue Guan Bing Za Zhi
October 2007
Objective: To observe the prevalence of J wave in apparently healthy subjects in Wuhan.
Methods: The study subjects comprised of 1817 apparently healthy subjects (1131 males, mean age 46.38 +/- 15.
Aim: To evaluate the safety and bioactivity of catheter-mediated intracoronary gene delivery of naked plasmid DNA encoding human atrial natriuretic factor (hANF).
Methods: hANF gene delivery was performed in 12 canines. For each canine, 4 mg of reconstructed naked plasmid DNA encoding hANF (pCR3*hANF, n=6) or pCR3 (n=6, control) in 2 mL normal saline was injected into left coronary artery via a coronary angiographic catheter.