Serum immunoreactivity of SMP30 and its tissues expression in hepatocellular carcinoma.

Objectives: To detect serum antibody against SMP30 in HCC patients and to evaluate its potential associations with HCC patient's clinical parameter and expression levels in HCC tissues.

Design And Methods: Serum antibody to SMP30 was tested by ELISA method; SMP30 mRNA and protein expression in HCC patients were analyzed using the methods of in situ nucleic acid hybridization and immunohistochemistry, respectively.

Results: The highest relevance of SMP30 antibody was associated with HCC (32.