- Glucocorticoid (GC) therapy can effectively treat serious inflammatory disorders but carries risks of side effects, requiring the lowest effective dose for the shortest duration to minimize these risks.
- Tapering GC therapy is crucial to avoid adrenal insufficiency by allowing the hypothalamic-pituitary-adrenal (HPA) axis to recover while monitoring for disease reactivation; higher doses can be tapered quickly, but once close to physiologic doses, tapering must slow down.
- Patients on GCs need to be aware of potential adrenal crisis during illnesses and should increase their doses accordingly while carrying a steroid alert card to inform healthcare providers.
Burkholderia pseudomallei is the causative agent of melioidosis. It is endemic in South East Asian countries and North Australia. Sporadic cases of melioidosis have been reported from several parts of South India.