A novel pyrazole bearing imidazole frame as ratiometric fluorescent chemosensor for Al/Fe ions and its application in HeLa cell imaging.

New pyrazole bearing imidazole derivative was successfully synthesized and thoroughly characterized by various spectroanalytical techniques. The sensor DIBI shows a highly selective and sensitive fluorescent response with the addition of Al/Fe ions in acetonitrile-water mixture. The strong fluorescent molecule exhibits a notable ratiometric emissions at 462 nm and 470 nm for Al and Fe ions, respectively (λ = 280 nm).

A highly sensitive and selective Schiff-base probe as a colorimetric sensor for Co and a fluorimetric sensor for F and its utility in bio-imaging, molecular logic gate and real sample analysis.

In this work, we designed a novel Schiff-base probe from the condensation reaction of 3,5-diiodosalicylaldehyde with isoniazid. Treatment of the sensor molecule with different metal ions like K, Ba, Ca, Mg, Fe, Mn, Co, Cu, Cd, Ni, Hg, Zn, Pb and Al in visual inspection and absorption measurements explained its colorimetric sensing ability. The sensor DISN displays a remarkable color variation from pale yellow to brownish-orange towards Co ion.

Execution of julolidine based derivative as bifunctional chemosensor for Zn and Cu ions: Applications in bio-imaging and molecular logic gate.

A simple julolidine based chemosensor (JT) was designed and synthesized by single condensation step. JT displayed excellent selectivity and sensitivity with on-off responses towards Zn and Cu over other biologically relevant metal ions in aqueous media. Upon addition of Zn ions, JT exhibited a significant blue shift in emission followed by turn-on enhancement while with Cu, the fluorescence intensity of JT was completely vanished.