Effective removal of chromium by adsorption using Delonix regia bark derived activated carbon from aqueous solution: a sustainable approach.

This study introduces a new biosorbent derived from Delonix regia bark-activated carbon to efficiently remove Chromium Cr(VI) metal ions from aqueous systems. The biosorbent was synthesized from the bark powder of the plant species and chemically activated with phosphoric acid. The biosorbent was characterized using FTIR, SEM, and BET to determine its functional properties and structural morphology.

A Rare Presentation of Guillain-Barré Syndrome With Associated Horner Syndrome: A Case Report.

Guillain-Barré syndrome (GBS) is an acute inflammatory polyradiculoneuropathy involving the peripheral nervous system. Autonomic dysfunctions are well-known complications of GBS and are major contributors to mortality. Autonomic dysfunctions are classically described during the acute phase of illness.

Identifying entrustable professional activities for MD program in biochemistry-A modified Delphi approach.

Entrustable professional activities (EPAs) facilitate competency-based assessments. India is on the verge of implementing competency-based training for postgraduate programs. MD degree in Biochemistry is a unique program available exclusively in India.

Revitalization of small millets for nutritional and food security by advanced genetics and genomics approaches.

Small millets, also known as nutri-cereals, are smart foods that are expected to dominate food industries and diets to achieve nutritional security. Nutri-cereals are climate resilient and nutritious. Small millet-based foods are becoming popular in markets and are preferred for patients with celiac and diabetes.

A novel pyrazole bearing imidazole frame as ratiometric fluorescent chemosensor for Al/Fe ions and its application in HeLa cell imaging.

New pyrazole bearing imidazole derivative was successfully synthesized and thoroughly characterized by various spectroanalytical techniques. The sensor DIBI shows a highly selective and sensitive fluorescent response with the addition of Al/Fe ions in acetonitrile-water mixture. The strong fluorescent molecule exhibits a notable ratiometric emissions at 462 nm and 470 nm for Al and Fe ions, respectively (λ = 280 nm).

Investigating the prospects of bacterial biosurfactants for metal nanoparticle synthesis - a comprehensive review.

Establishing biological synthesis of nanoparticles is increasing nowadays in the field of nanotechnology. The search for an optimal source with durability, stability, capacity to withstand higher environmental conditions with excellent characteristics is yet to meet. Consequently, there is need to create an eco-friendly strategy for metal nanoparticle synthesis.

Execution of julolidine based derivative as bifunctional chemosensor for Zn and Cu ions: Applications in bio-imaging and molecular logic gate.

A simple julolidine based chemosensor (JT) was designed and synthesized by single condensation step. JT displayed excellent selectivity and sensitivity with on-off responses towards Zn and Cu over other biologically relevant metal ions in aqueous media. Upon addition of Zn ions, JT exhibited a significant blue shift in emission followed by turn-on enhancement while with Cu, the fluorescence intensity of JT was completely vanished.

Lateral Parapatellar Approach Without Tibial Tubercle Osteotomy for Fixed Valgus Deformity Correction in Total Knee Arthroplasty.

Introduction: The lateral parapatellar approach provides direct access to the pathological area in a valgus knee deformity and allows sequential titrated release of contracted lateral soft tissues during total knee arthroplasty.

Step 1 Preoperative Planning: Differentiate the flexible and fixed components of the valgus deformity by clinical and radiographic examination.

Step 2 Expansile Lateral Arthrotomy: Open the knee joint from the lateral side by coronal z-plasty of the lateral retinaculum, oblique lateral tenotomy of the quadriceps tendon, and iliotibial band release.

Efficacy and mid term results of lateral parapatellar approach without tibial tubercle osteotomy for primary total knee arthroplasty in fixed valgus knees.

The lateral parapatellar approach, despite providing direct access to the pathological area has not been widely accepted for knee arthroplasty in valgus deformities. We performed a modified lateral (Keblish) approach which consisted of coronal z plasty of lateral retinaculum, quadriceps snip, titrated sequential lateral release and closure with expanded lateral structures in 32 arthritic fixed valgus knees. In 30 knees, either tendon of popliteus or lateral collateral ligament or both could be preserved.

Orthodontic and orthognathic management of a complex mandibular asymmetry.

The application of a combined surgical-orthodontic procedure for the treatment of major facial deformities (eg, asymmetries) and associated malocclusions has become an increasingly prevalent treatment modality over the past few decades. Development of sound conjoint treatment principles made possible the correction of skeletal and dental dysplasias that were unyielding to either surgical or orthodontic treatment alone. The presence and severity of dentofacial asymmetries has been the subject of many commentaries and investigations.

MiR-378 controls cardiac hypertrophy by combined repression of mitogen-activated protein kinase pathway factors.

Background: Several microRNAs (miRs) have been shown to regulate gene expression in the heart, and dysregulation of their expression has been linked to cardiac disease. miR-378 is strongly expressed in the mammalian heart but so far has been studied predominantly in cancer, in which it regulates cell survival and tumor growth.

Methods And Results: Here, we report tight control of cardiomyocyte hypertrophy through miR-378.

Deficiency of CD73/ecto-5'-nucleotidase in mice enhances acute graft-versus-host disease.

Extracellular ATP and adenosine have immunoregulatory roles during inflammation. Elevated extracellular ATP is known to exacerbate GVHD, and the pharmacologic activation of the adenosine A2A receptor is protective. However, the role of endogenous adenosine is unknown.

Graft-versus-host disease is enhanced by extracellular ATP activating P2X7R.

Danger signals released upon cell damage can cause excessive immune-mediated tissue destruction such as that found in acute graft-versus-host disease (GVHD), allograft rejection and systemic inflammatory response syndrome. Given that ATP is found in small concentrations in the extracellular space under physiological conditions, and its receptor P2X(7)R is expressed on several immune cell types, ATP could function as a danger signal when released from dying cells. We observed increased ATP concentrations in the peritoneal fluid after total body irradiation, and during the development of GVHD in mice and in humans.

Lack of the purinergic receptor P2X(7) results in resistance to contact hypersensitivity.

Sensitization to contact allergens requires activation of the innate immune system by endogenous danger signals. However, the mechanisms through which contact allergens activate innate signaling pathways are incompletely understood. In this study, we demonstrate that mice lacking the adenosine triphosphate (ATP) receptor P2X(7) are resistant to contact hypersensitivity (CHS).

Duplication of the rectum: report of four cases and review of the literature.

Rectal duplications are rare anomalies. Recently, we observed four cases of rectal duplication, each presenting with different clinical features including chronic constipation, a prolapsing rectal "polyp, " a "growth" from the vulva, and acute retention of urine. The variety of clinical presentations may lead to delay in diagnosis and multiple operations.

Occurrence of human rabies in peninsular Malaysia.

The occurrence of a case of human rabies in Peninsular Malaysia is reported. Despite the various control measures taken, sporadic cases of rabies have continued to occur in Peninsular Malaysia, especially in the northern states. Clinical awareness of the occurrence of rabies is therefore important and effective post-exposure prophylaxis should be instituted as soon as possible to prevent the possible occurrence of this dreaded disease.

The spectrum of histologically diagnosed malignant neoplasms in Sabah, 1983-1988.

Malignant neoplasms diagnosed histologically in the state of Sabah during the period November 1983 to October 1988 were analysed to determine the distribution of malignant neoplasms according to site, age, sex and major ethnic groups. The five commonest malignant neoplasms in males were carcinomas of the nasopharynx, stomach, skin, lung and liver. In females the five commonest malignant neoplasms were carcinomas of the cervix uteri, breast, ovary, thyroid and skin.

Mycobacterium leprae reactive T cell clones from lepromatous leprosy patients after prolonged dapsone chemotherapy.

The proliferative responses of peripheral blood mononuclear cells (PBMC) to Mycobacterium leprae and BCG were studied in two groups of leprosy patients: a group of 8 lepromatous patients who had been on treatment for more than 20 years (TLL) and a group of 8 untreated lepromatous leprosy patients (ULL). The mean response to M. leprae of the TLL group was 6195 cpm with 5 of the 8 patients responding positively.

Association of ABO and Rh(D) blood groups with filariasis.

ABO and Rh blood groups in 344 filarial patients and 320 controls matched with respect to age, community and residence are reported. An excess of B and a deficiency of AB was observed among the filarial patients. The relative risks for the B and AB were 1.

Arylesterase isoenzymes and activity in normal healthy adults and in patients with cancer and with other diseases.

Serum arylesterase isozyme patterns were studied in 184 normal healthy individuals, 290 cancer patients and 466 patients with various diseases. No abnormal patterns were seen in the normal healthy subjects. Several abnormal patterns found in the group of cancer patients and patients with various diseases are described.