ICT-based fluorescent nanoparticles for selective cyanide ion detection and quantification in apple seeds.

In this report, we successfully engineered a novel probe based on an acceptor-donor-acceptor (A-D-A) architecture featuring dicyanovinyl-substituted thieno[3,2-]thiophene, termed DCVTT. The designed probe self-assembles into luminous nanoparticles (DCVTT NPs) upon introducing mixed aqueous solutions. These fluorescent nanostructures served as a ratiometric probe for detecting cyanide (CN) ions in aqueous-based environments, owing to the robust Intramolecular Charge Transfer (ICT) characteristics of DCVTT.

F NMR Probes: Molecular Logic Material Implications for the Anion Discrimination and Chemodosimetric Approach for Selective Detection of HO.

Detection and discrimination of similar solvation energies of bioanalytes are vital in medical and practical applications. Currently, various advanced techniques are equipped to recognize these crucial bioanalytes. Each strategy has its own benefits and limitations.

Quantifying CO-release from a photo-CORM using F NMR: An investigation into light-induced CO delivery.

Carbon monoxide (CO) is an innate signaling molecule that can regulate immune responses and interact with crucial elements of the circadian clock. Moreover, pharmacologically, CO has been substantiated for its therapeutic advantages in animal models of diverse pathological conditions. Given that an excessive level of CO can be toxic, it is imperative to quantify the necessary amount for therapeutic use accurately.

TiO supported pallidum-bipyridyl complex as an efficient catalyst for Suzuki-Miyaura reaction in aqueous-ethanol.

Owing to their improved catalytic stability and ability to undergo repeated cycles, solid-supported catalysts show great potential for various catalytic reactions. In this study, we synthesized a catalyst comprising a palladium-2,2-bipyridine complex supported on TiO nanoparticles (TiO@BDP-PdCl) fully characterised and investigated its efficacy in Suzuki-Miyaura cross coupling reactions involving phenyl boronic acid with various aryl halides under mild reaction conditions. The 2,2'- bipyridine (bp) has shown excellent complexation properties for Pd (II) and it could be easily anchored onto functionalized TiO support by the bridging carboxylate ions.

Lysosome targeted visible light-induced photo-CORM for simultaneous CO-release and singlet oxygen generation.

We report a specific lysosome targeted light-responsive CO-releasing molecule (Lyso-CORM). Lyso-CORM is very stable under dark conditions. CO and singlet oxygen (O) generation was effectively triggered under one photon and two photon excitation (800 nm) conditions.

Recent Advances in Drug Release, Sensing, and Cellular Uptake of Ring-Opening Metathesis Polymerization (ROMP) Derived Poly(olefins).

The synthesis and applications of ring-opening metathesis polymerization (ROMP) derived poly(olefins) have emerged as an exciting area of great interest in the field of biomaterials science. The major focus of this mini-review is to present recent advances in the synthesis of functional materials using ROMP-derived poly(olefins) utilized for drug release, sensing, and cellular uptake in the past seven years (2015-2022). This review reveals that materials synthesized by ROMP-derived well-defined functional poly(olefins) stand to be highly promising systems for medical as well as biological studies.

Multifunctional rhodamine B appended ROMP derived fluorescent probe detects Al and selectively labels lysosomes in live cells.

There a few reports of rhodamine-based fluorescent sensors for selective detection of only Al, due to the challenge of identifying a suitable ligand for binding Al ion. The use of fluorophore moieties appended to a polymer backbone for sensing applications is far from mature. Here, we report a new fluorescent probe/monomer 4 and its ROMP derived polymer P for specific detection of Al ions.

Green Light-Responsive CO-Releasing Polymeric Materials Derived from Ring-Opening Metathesis Polymerization.

Carbon monoxide (CO) is an important biological gasotransmitter in living cells. Precise spatial and temporal control over release of CO is a major requirement for clinical application. To date, the most reported carbon monoxide releasing materials use expensive fabrication methods and require harmful and poorly designed tissue-penetrating UV irradiation to initiate the CO release precisely at infected sites.

Two-Photon-Induced CO-Releasing Molecules as Molecular Logic Systems in Solution, Polymers, and Cells.

Phototherapeutic applications of carbon monoxide (CO)-releasing molecules are limited because they require harmful UV and blue light for activation. We describe two-photon excitation with NIR light (800 nm)-induced CO-release from two Mn tricarbonyl complexes bearing 1,8-naphthalimide units (1, 2). Complex 2 behaves as a logic OR gate in solution, nonwovens, and in HeLa cells.

Remote-controlled delivery of CO via photoactive CO-releasing materials on a fiber optical device.

Although carbon monoxide (CO) delivery materials (CORMAs) have been generated, remote-controlled delivery with light-activated CORMAs at a local site has not been achieved. In this work, a fiber optic-based CO delivery system is described in which the photoactive and water insoluble CO releasing molecule (CORM) manganese(i) tricarbonyl [(OC)3Mn(μ3-SR)]4 (R = nPr, 1) has been non-covalently embedded into poly(l-lactide-co-d/l-lactide) and poly(methyl methacrylate) non-woven fabrics via the electrospinning technique. SEM images of the hybrid materials show a porous fiber morphology for both polymer supports.