Synopsis of recent research by authors named "Gananadhamu Samanthula"
- Gananadhamu Samanthula's recent research primarily focuses on the stability and degradation characterization of various pharmaceutical compounds, utilizing advanced analytical techniques such as liquid chromatography (LC), high-resolution mass spectrometry (HRMS), and nuclear magnetic resonance (NMR) spectroscopy.
- His studies encompass a range of compounds, including upadacitinib, ubrogepant, mavacamten, and baricitinib, where he investigates their forced degradation profiles, identifies impurities, and assesses their toxicity and mutagenicity through in silico models.
- Samanthula also explores innovative drug formulations, such as co-amorphous sulpiride, and highlights the potential of covalent organic frameworks in enhancing drug stability and separation processes, emphasizing a multi-faceted approach to improving drug safety and effectiveness.
