Zinc(II) Complexes Derived from Schiff Bases: Syntheses, Structures, and Biological Activity.

Three new zinc(II) complexes, [Zn2I2(L1)2] (1), [Zn(HL2)2(NCS)2] (2), and [ZnIL3] (3), where L1 is the anionic form of 2-[(6-methylpyridin-2-ylimino)methyl]phenol (HL1), HL2 is the zwitterionic form of 2-(cyclopropyliminomethyl)-5-fluorophenol (HL2), and L3 is the anionic form of 5-bromo-2-[(3-morpholin-4-ylpropylimino)methyl]phenol (HL3), have been prepared and characterized by elemental analyses, IR, UV and NMR spectra, and single crystal X-ray crystallographic determination. Complex 1 is a dinuclear zinc complex, and complexes 2 and 3 are mononuclear zinc complexes. The Zn atoms in the complexes are in tetrahedral coordination.

Syntheses, Crystal Structures, Antimicrobial Activity and Thermal Behavior of Copper(II) Complexes Derived from 1-Naphthylacetic Acid and Diamines.

Two copper(II) complexes, [CuL2(EA)] (1) and [Cu2L4(PA)2]·2H2O (2·2H2O), where L is 1-naphthylacetate, EA is N,N-diethylethane-1,2-diamine, PA is propane-1,3-diamine, have been prepared and characterized. Structures of the complexes have been characterized by single-cyrstal X-ray diffraction. Complex 1 is a mononuclear copper(II) compound, with the Cu atoms coordinated in square planar geometry.

Synthesis, Crystal Structures and Catalytic Oxidation of Manganese(III) Complexes Derived from Salen-Type Schiff Base N,N'-Bis(5-nitrosalicylidene)ethane-1,2-diamine.

Two mononuclear Schiff base manganese(III) complexes, [MnL(N3)(OH2)]·CH3OH (1) and [MnL(NCS)(OH2)] · H2O (2), where L is the dianionic form of N,N'-bis(5-nitrosalicylidene)ethane-1,2-diamine, have been prepared and characterized by elemental analysis, IR and UV-Vis spectroscopy and single crystal X-ray diffraction. The Mn atom in each complex is in an octahedral coordination. Molecules of the complexes are linked through intermolecular hydrogen bonds.

catena-Poly[[[(3,5-dimethyl-1H-pyrazole)-copper(II)]-μ-{N-[1-(2-oxidophen-yl)ethyl-idene]-l-valinato}] methanol monosolvate].

The asymmetric unit of the title compound, {[Cu(C(13)H(15)NO(3))(C(5)H(8)N(2))]·CH(3)OH}(n), contains two complex mol-ecules and two solvent mol-ecules. Each Cu(II) ion is in a distorted square-pyramidal coordination with one N and two O atoms from the Schiff base ligand and one N atom from the heterocycle in the basal positions and one carboxyl-ate O atom from a neighbouring ligand in the apical position. The apical Cu-O bonds are much longer than the basal Cu-O and Cu-N bonds.

Bis{2-[3-(dimethyl-ammonio)-propyl-imino-methyl-κN]-6-meth-oxy-phenolato-κO}bis-(thio-cyanato-κN)nickel(II).

The asymmetric unit of the title complex, [Ni(NCS)(2)(C(13)H(20)N(2)O(2))(2)], consists of two half-mol-ecules, both of which are completed by crystallographic inversion symmetry (Ni(2+) site symmetry = in both cases). Both metal ions are six-coordinated in distorted trans-NiO(2)N(4) geometries arising from two N,O-bidentate Schiff base ligands and two N-bonded thio-cyanate ions. The mol-ecular conformations are reinforced by two intra-molecular N-H⋯O hydrogen bonds.

catena-Poly[[{2-[(2-hy-droxy-eth-yl)imino-meth-yl]-6-meth-oxy-phenolato}copper(II)]-μ-thio-cyanato].

In the title thio-cyanate-bridged polynuclear copper(II) complex, [Cu(C(10)H(12)NO(3))(NCS)](n), the Cu atom is five-coordinated in a square-pyramidal geometry, with one phenolato O, one imino N and one hy-droxy O atom of a Schiff base ligand and one thio-cyanato N atom defining the basal plane, and with one thio-cyanato S atom occupying the apical position. In the crystal structure, pairs of adjacent complex mol-ecules are linked through inter-molecular O-H⋯O hydrogen bonds into dimers. The dimers are further linked via Cu⋯S inter-actions, forming two-dimensional layers parallel to the bc plane.

{3-Methyl-2-[(1-oxido-2-naphth-yl)methyl-idene-amino-κO,N]butano-ato-κO}(1H-pyrazole-κN)nickel(II).

In either of the two independent mol-ecules within the asymmetric unit of the title compound, [Ni(C(16)H(15)NO(3))(C(3)H(4)N(2))], the Ni(II) atom is coordinated by the two N atoms and two O atoms in a distorted square-planar geometry. The crystal packing is stabilized by strong and weak inter-molecular C-H⋯O hydrogen bonds, as well as weak centroid-centroid π-stacking inter-actions [centroid-centroid separation = 3.526 (3) Å].

{N,N-Dimethyl-N'-[1-(2-pyrid-yl)ethyl-idene]propane-1,3-diamine}bis(thio-cyanato-κN)-copper(II).

In the title complex, [Cu(NCS)(2)(C(12)H(19)N(3))], the Cu(II) atom is five-coordinated in a square-pyramidal geometry defined by one pyridine N, one imine N, and one amine N atom of the tridentate Schiff base ligand and two N-bonded thio-cyanate ions (one of the latter occupying the apical site). The three bridging C atoms and the two terminal C atoms of the Schiff base are disordered over two sets of sites, with occupancies of 0.465 (2) and 0.

Aqua-{N-[1-(2-oxidophen-yl)ethyl-idene]-l-serinato}copper(II) monohydrate.

In the title compound, [Cu(C(11)H(11)NO(4))(H(2)O)]·H(2)O, each Cu(II) ion is four-coordinated by one N and two O atoms from the tridentate Schiff base ligand, and by one O atom from the coordinated water mol-ecule in a distorted square-planar geometry. Inter-molecular O-H⋯O hydrogen bonds link complex mol-ecules and solvent water mol-ecules into flattened columns propagated in [100].

Benzyl 3-(10-oxo-9,10-dihydrophenanthren-9-ylidene)dithiocarbazate.

In the title compound, C(22)H(16)N(2)OS(2), the phenanthrene ring is nearly perpendicular to the phenyl ring, making a dihedral angle of 87.2 (2)°. Intra-molecular N-H⋯O inter-actions are present.

(2-Acetyl-phenolato)(2,2'-bipyridine)nitratocopper(II).

In the title compound, [Cu(C(8)H(7)O(2))(NO(3))(C(10)H(8)N(2))], the Cu(II) ion is five-coordinate in a distorted square-pyramidal geometry. The basal positions are occupied by two N atoms from a 2,2'-bipyridine ligand and two O atoms from the 2-acetyl-phenolate anion. The axial position is occupied by one O atom of a nitrate anion.

catena-Poly[[pyridinecopper(II)]-μ-N-[(2-oxido-1-naphth-yl)methyl-ene]glycinato].

In the title compound, [Cu(C(13)H(9)NO(3))(C(5)H(5)N)], the Cu(II) atom is coordinated in a distorted square-pyramidal geometry, with two N and two O atoms in the basal positions and one O atom in the apical position. The apical Cu-O bond [2.3520 (16) Å] is much longer than the basal Cu-O and Cu-N bonds [1.

(2,2'-Bipyridine-κN,N'){N-[2-oxido-5-(phenyl-diazen-yl)benzyl-idene-κO]glycinato-κN,O}copper(II).

In the title compound, [Cu(C(15)H(11)N(3)O(3))(C(10)H(8)N(2))], the Cu(II) atom is five-coordinated in a distorted square-pyramidal CuN(3)O(2) geometry. The basal positions are occupied by three donor atoms from the tridentate Schiff base ligand and by one N atom from the 2,2'-bipyridine ligand. The axial position is occupied by the other N atom of the 2,2'-bipyridine ligand.

[Bis(3,5-dimethyl-pyrazol-1-yl)methane]{N-[1-(2-oxidophen-yl)ethyl-idene]-dl-alaninato}copper(II) monohydrate.

In the title compound, [Cu(C(11)H(11)NO(3))(C(11)H(16)N(4))]·H(2)O, the Cu(II) atom is five-coordinate in a distorted square-pyramidal geometry. The basal positions are occupied by three donor atoms from the tridentate Schiff base ligand and by one N atom from a bis-(3,5-dimethyl-prazol-l-yl)methane ligand. The apical position is occupied by the N atom of the other ligand of this type.

N'-(3-Bromo-5-chloro-2-hydroxy-benzyl-idene)-4-hydr-oxybenzohydrazide.

The mol-ecule of the title compound, C(14)H(10)BrClN(2)O(3), is planar [dihedral angle between the aromatic rings = 3.0 (2)°] and shows a trans configuration with respect to the C=N double bond. The crystal structure is stabilized by inter-molecular N-H⋯O hydrogen bonds and an intramolecular O-H⋯N interaction also occurs.

(Imidazole-κN){N-[1-(2-oxidophenyl)ethylidene]-l-valinato-κO,N,O'}copper(II).

In each of the two independent mol-ecules in the asymmetric unit of the title compound, [Cu(C(13)H(15)NO(3))(C(3)H(4)N(2))], the Cu(II) atom is four-coordinated by two O atoms and the N atom of the tridentate Schiff base ligand and one N atom from the imidazole ligand in a distorted square-planar geometry. In the crystal structure, mol-ecules are linked by inter-molecular N-H⋯O hydrogen bonds.

(1H-Imidazole-κN) {N-[1-(2-oxidophenyl-κO)ethyl-idene]-l-phenyl-alaninato-κN,O}copper(II).

In the title compound, [Cu(C(17)H(15)NO(3))(C(3)H(4)N(2))], the Cu(II) atom is four-coordinated by two O atoms and the N atom of the tridentate Schiff base ligand, and one N atom from the imidazole ligand in a distorted square-planar geometry. In the crystal structure, mol-ecules are linked into dimers by inter-molecular N-H⋯O hydrogen bonds.

Bis(3,5-dimethyl-pyrazole)[N-salicyl-idene-β-alaninato(2-)]copper(II) dihydrate.

In the title compound, [Cu(C(10)H(10)NO(3))(C(5)H(8)N(2))(2)]·2H(2)O, the Cu(II) atom is coordinated by three N atoms and two O atoms in a distorted square-pyramidal geometry. The crystal packing is stabilized by inter-molecular O-H⋯O and N-H⋯O hydrogen bonds.