Publications by authors named "Gampa Sandeep"
Mutations in the mitochondrial DNA maintenance gene POLG (DNA Polymerase Gamma, Catalytic Subunit), encoding mitochondrial DNA polymerase gamma (pol γ), are associated with an extremely broad phenotypic spectrum. We identified homozygous POLG c.1879C>T; p.
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- Sjogren's syndrome (SS) is an autoimmune disease that can affect various organs, including the peripheral nervous system, leading to different types of neuropathy symptoms.
- A study analyzed 21 SS patients with peripheral neuropathy over six years, revealing that most had neuropathy as their first symptom, with specific patterns such as mononeuropathy multiplex and ganglionopathy being common.
- Key diagnostic tools included serology tests for specific antibodies, Schirmer's test for eye function, and nerve biopsies, which helped distinguish SS from other conditions.
Background: As per the current recommendations, carotid interventional procedures (carotid endarterectomy/carotid artery stenting) are considered superior to medical management in reducing the stroke recurrence in patients with symptomatic extracranial internal carotid artery (ICA) stenosis.
Objective: The objective of this study is to compare the best medical management with carotid interventional procedures in the prevention of stroke recurrence in the patients with symptomatic extracranial ICA stenosis.
Materials And Methods: This was a parallel, prospective, two-arm, open-label, observational study.