Publications by authors named "Galyna Fadieienko"

Article Synopsis
  • Bismuth quadruple therapies (BQTs) have been effective in treating Helicobacter pylori infections in Europe, particularly in the face of antibiotic resistance, with notable use increasing from 8.6% in 2013 to 39% in 2021.
  • An analysis of data from nearly 50,000 patients indicated that the single-capsule BQT was the most common regimen and achieved over 90% effectiveness with certain combinations.
  • Key factors that improved treatment success included adherence to the regimen, use of high-dose proton pump inhibitors, and implementing the therapy as a first-line treatment.
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Article Synopsis
  • A study examined how different reasons for testing for Helicobacter pylori (H. pylori) affect treatment prescriptions and their success rates across Europe from 2013 to 2023.
  • Out of 53,636 cases, the most common reasons for testing included dyspepsia with normal endoscopy and various types of ulcers, with treatment effectiveness ranging from 87% to 91% based on the indication.
  • Patients with ulcers and preneoplastic lesions experienced higher treatment success and compliance, while those tested for dyspepsia had higher rates of adverse effects.
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Objective: The aim: To analyze the status of Gut microbiota (GM) at the level of the main phylotypes in patients with NAFLD, depending on the body mass index (BMI) and gender in comparison with a group of practically healthy individuals.

Patients And Methods: Materials and methods: The study involved 120 patients with NAFLD, who were divided into two groups depending on BMI and the control group containing 20 practically healthy individuals.

Results: Results: In patients with NAFLD with comorbid obesity, a statistically significant increase in the relative amount of Firmicutes (52.

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Background: Hereditary component plays a significant role in the formation of insulin resistance (IR) - one of the pathogenetic links of arterial hypertension (AH) and type 2 diabetes mellitus (DM2). However, the genetic predisposition to IR can not be realized and does not manifest itself clinically in the absence of appropriate factors of the environment (excessive nutrition, low physical activity, etc.).

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Unlabelled: Glycerol phenylbutyrate (GPB) lowers ammonia by providing an alternate pathway to urea for waste nitrogen excretion in the form of phenylacetyl glutamine, which is excreted in urine. This randomized, double-blind, placebo-controlled phase II trial enrolled 178 patients with cirrhosis, including 59 already taking rifaximin, who had experienced two or more hepatic encephalopathy (HE) events in the previous 6 months. The primary endpoint was the proportion of patients with HE events.

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