Influence of base designs on the manufacturing accuracy of vat-polymerized diagnostic casts using two different technologies.

Statement Of Problem: Diagnostic casts can incorporate different base designs and be manufactured using different vat-polymerization technologies. However, the influence of the interrelation between the base design and the 3D printing technology on the casts' final accuracy remains unclear.

Purpose: The purpose of this in vitro study was to assess the influence of different base designs of 3D printed casts on the accuracy of 2 vat-polymerization technologies.

OralImmunoAnalyser: a software tool for immunohistochemical assessment of oral leukoplakia using image segmentation and classification models.

Oral cancer ranks sixteenth amongst types of cancer by number of deaths. Many oral cancers are developed from potentially malignant disorders such as oral leukoplakia, whose most frequent predictor is the presence of epithelial dysplasia. Immunohistochemical staining using cell proliferation biomarkers such as ki67 is a complementary technique to improve the diagnosis and prognosis of oral leukoplakia.

Accuracy assessment (trueness and precision) of a confocal based intraoral scanner under twelve different ambient lighting conditions.

Objectives: The ambient lighting condition has been identified as an important factor that influences the accuracy of intraoral scanners (IOSs). The purpose of this study was to evaluate the influence of 12 different ambient lighting conditions on the accuracy of a confocal based IOS (PrimeScan).

Materials And Methods: A typodont was digitized using a laboratory scanner (L2i) to obtain a reference standard tessellation language (STL) file.

Importance of the vaporization margin during CO laser treatment of oral leukoplakia: A survival study.

Objectives: The main purpose of this study was to assess the response of oral leukoplakia to CO laser vaporization treatment, as well as determining possible factors that may affect recurrence of lesions.

Materials And Methods: A retrospective study was conducted, in which the medical records of patients who had been clinically and histologically diagnosed with oral leukoplakia and treated with CO laser between 1996 and 2019 at the Oral Medicine Teaching Unit of the Faculty of Dentistry of the University of Santiago de Compostela were reviewed.

Results: Fifty-eight patients were included: 36 female and 22 male subjects, with a mean age of 63.

Efficacy of different sentinel lymph node biopsy protocols in oral squamous cell carcinoma: Systematic review and meta-analysis.

The sentinel node biopsy (SNB) is highly protocolized in other cancers, however, this is not the case for oral squamous cell carcinoma patients, hence our objective was to evaluate the different protocols published. A specific study protocol was designed and subsequently registered on PROSPERO (Ref. CRD42021279217).

Efficacy of photobiomodulation in reducing pain and improving the quality of life in patients with idiopathic burning mouth syndrome. A systematic review and meta-analysis.

Burning mouth syndrome is a chronic condition, which is characterised by a burning sensation or pain in the mucosa of the oral cavity. Treatment options include antidepressants, antipsychotics, anticonvulsants, analgesics, hormone replacement therapies and more recently photobiomodulation. This study aims to perform a systematic review with meta-analysis in order to determine the effect of photobiomodulation on pain relief and the oral health-related quality of life associated with this condition.

Prognostic value of CAIX expression in oral squamous cell carcinoma: a systematic review and meta-analysis.

Carbonic anhydrase IX (CAIX) is a hypoxia-related protein considered as a predictor for oral squamous cell carcinoma (OSCC) biological behaviour. Nevertheless, this prognostic value is still yet to be validated. We aim to quantify prognostic significance of CAIX overexpression in OSCC by meta-analysis.

Using a repositioning splint to determine reproducibility in the color registers of a dental spectrophotometer.

Objectives: The purpose of this study was to assess if the use of intraoral positioning guides could increase the reproducibility of color measurements with a dental spectrophotometer.

Methods: Twenty-three subjects were selected, and positioning guides for the maxillary arch of each participant were fabricated with clear 4 mm thermo-sheets. One orifice was made in the center of the clinical crown of the upper-right central incisor and another in the canine, with an external 6 mm diameter trephine.

Exosomes in head and neck cancer. Updating and revisiting.

Exosomes have gone from being considered simple containers of intracellular waste substances to be considered important carriers of cellular signals. Its broad capacity to promote tumour growth, both and metastatic, has greatly intensified scientific research on them. In the same way and depending on its content, its tumour suppressive properties have opened a window of light and hope in the fight against cancer.

A Pilot Clinical Study on the Prognostic Relevance of Plasmatic Exosomes Levels in Oral Squamous Cell Carcinoma Patients.

Background: To evaluate the relationship between the plasmatic CD63 and CAV1 positive exosome levels, in patients with OSCC before and after surgical treatment and to correlate it with their overall survival.

Methods: A double-blind pilot study over 10 patients OSCC and T4 stage without distant metastases or local bone invasion has been performed. The average follow-up period was 37.

20 years of alveolar distraction: A systematic review of the literature.

Background: The Vertical Alveolar Distraction Osteogenesis (VADO) technique is an excellent solution for bone and soft tissue neoformation in areas in which there has been significant bone atrophy that hinders normal rehabilitation using dental implants. The goal of this systematic review is to analyze the most relevant articles published on VADO in the literature over the past 20 years.

Material And Methods: The review was performed by using the keywords: "alveolar ridge", "distraction ostegenesis" and "dental implant".

Evaluation of a new tricalcium phosphate for guided bone regeneration: an experimental study in the beagle dog.

This study compared the in vivo behavior of two biomaterials, xenograft (Bio-Oss) and alloplastic tricalcium phosphate (Sil-Oss), vs a control (no biomaterial) in beagle dogs treated with guided bone regeneration (GBR). Six male adult beagle dogs were included. The third and fourth mandibular premolars and first mandibular molars (3P3, 4P4 and 1M1) on both sides were extracted.

Survival study of leukoplakia malignant transformation in a region of northern Spain.

Background: Oral leukoplakia is the most common potentially malignant disorder (PMD) of the oral cavity. The objectives of this study are to determine the clinicopathologic features in a group of patients with oral leukoplakia of Northern Spain (Galicia), determining the factors associated to clinical risk and analyzing the malignant transformation of these patients.

Material And Methods: We included 85 patients.

Differential expression of snoRNAs in oral squamous cell carcinomas: new potential diagnostic markers.

Background: Small nucleolar RNAs (snoRNAs) are small non-coding RNA sequences whose most studied function is ribosome biogenesis. The altered expression of snoRNA is observed in tumoral processes such as breast cancer and multiple myeloma. However, we have not found any references to snoRNAs in oral squamous cell carcinomas (OSCC) in the literature at the time this article was written.

Update in the extraction of airway foreign bodies in adults.

Foreign body (FB) aspiration into the airway is lees common in adults than children. Nevertheless its incidence does not decrease through time. We present clinical relevant aspects of airway FBs on the basis of a selective review of pertinent literature retrieved by a search in the PubMed database.

The use of tissue microarrays for semiquantitative evaluation of ATPaseC1 expression is ineffective.

We described earlier the possible role of ATPaseC1 expression as a diagnostic and prognostic marker for oral cancer; others have reported its use for tumors of the lung and breast. We assessed ATPaseC1 expression in a sample of oral squamous cell carcinoma (OSCC) using tissue microarrays (TMAs) to analyze the relation between ATPaseC1 expression and clinical, histopathological and prognostic parameters. We performed a retrospective study of 48 cases of OSCC.

The use of CA-IX as a diagnostic method for oral leukoplakia.

The presence and degree of dysplasia are important diagnostic and prognostic criteria for oral leukoplakia, but evaluation of dysplasia is difficult and subjective. Carbonic anhydrase-IX (CA-IX) is expressed primarily in tumor cells and is considered a specific hypoxia marker. We investigated the role of CA-IX in oral leukoplakia.

Radiological infrabony defects after impacted mandibular third molar extractions in young adults.

Purpose: To estimate the prevalence of infrabony defects and their healing at the distal aspect of mandibular second molars (M2s) after extraction of impacted mandibular third molars (M3s).

Materials And Methods: This prospective clinical study included 22 young healthy patients (21.03 ± 4.

Mandibular second molar periodontal healing after impacted third molar extraction in young adults.

Purpose: To estimate the prevalence of preoperative periodontal defects and analyze 12-month spontaneous healing on the distal aspect of the mandibular second molar (M2) after impacted mandibular third molar (M3) extraction.

Materials And Methods: This prospective clinical study was conducted in 25 healthy young patients (21.03 ± 4.

Predictive factors for maxillary sinus augmentation outcomes: a case series analysis.

Aim: To determine the influence of different local and systemic factors on histologic, histomorphometric, and radiographic outcomes after maxillary sinus augmentation.

Materials And Methods: Fifty-two sinus augmentation procedures were performed. Grafting material consisted of a mixture of anorganic bovine bone (ABB) and autogenous bone.

Repeatability and accuracy of a paralleling technique for radiographic evaluation of distal bone healing after impacted third molar surgery.

Objectives: The purpose of this study was to investigate the repeatability and radiographic accuracy of an intraoral paralleling technique to evaluate periodontal bone healing on the distal surface of the second mandibular molar (2 Mm) after impacted third mandibular molar (3 Mm) surgical extraction.

Methods: In order to estimate the variation in different radiographs, three replicas were made, each from 2 Mm, totalling 69 radiographic radicular longitude (RRL) recordings. One operator performed the periapical radiographs in a standard manner, utilizing a modified posterior film holder for the radiographic technique of parallelism, applied on the posterior region with the X-ray beam focused on the centre of 2 Mm.

A three-dimensional computer model of the human mandible in two simulated standard trauma situations.

Purpose: A three-dimensional finite element model of the human mandible was developed to simulate and analyse biomechanical behaviour in two standard trauma situations. This computer-based study was made to assess the stress patterns within human mandibles generated by impact forces.

Material And Methods: The mandibular model was generated using 7.

Mandibular nerve paresthesia caused by endodontic treatment.

The paresthesias of the inferior dental nerve consists of a complication that can occur after performing various dental procedures such as cystectomies, extraction of impacted teeth, apicoectomies, endodontic treatments, local anesthetic deposition, preprosthetic or implantologic surgery. The possible mechanisms of nervous lesions are mechanical, chemical and thermal. Mechanical injury includes compression, stretching, partial or total resection and laceration.

Efficacy of chlorhexidine mouthrinses with and without alcohol: a clinical study.

Background: Plaque control is the main method for preventing periodontal diseases. Chlorhexidine digluconate mouthrinse is widely recognized as helping to maintain plaque control. Most of these mouthrinses contain alcohol, making them impractical for many patients, including those with oral mucosal hypersensitivity.