Publications by authors named "Galina V Trunova"
Article Synopsis
- - COVID-19 is a serious and contagious respiratory illness, leading to the search for new treatments, particularly looking into polysaccharides with antiviral potential.
- - The study focused on the antiviral effects of the drug "Immeran" against SARS-CoV-2 in hamsters, testing doses of 500 and 1000 μg/kg through intraperitoneal injections.
- - Results showed that Immeran effectively reduced virus replication in the lungs and, at the higher dose, prevented weight loss in hamsters, while also promoting the production of anti-SARS-CoV-2 antibodies, indicating it might enhance immune responses.
Destroying tumor vasculature is a relevant therapeutic strategy due to its involvement in tumor progression. However, adaptive resistance to approved antiangiogenic drugs targeting VEGF/VEGFR pathway requires the recruitment of additional targets. In this aspect, targeting TRAIL pathway is promising as it is an important component of the immune system involved in tumor immunosurveillance.
View Article and Find Full Text PDF