Placental morphometry and Doppler flow velocimetry in cases of chronic human fetal hypoxia.

Objective: To investigate the structural basis of abnormal Doppler waveforms in the utero-placental circulations in cases of chronic fetal hypoxia.

Study Design: Morphometric analysis was performed on placental samples from 58 pregnancies with abnormal Doppler waveforms in the uterine, placental and umbilical circulations at 32-34 weeks, and 10 pregnancies with normal waveforms.

Results: The volume of placental villi reduced from 350.