Publications by authors named "Galin Spicer"
Purpose: The Port Delivery System with ranibizumab (PDS) is approved in the United States for neovascular age-related macular degeneration. The United States Prescribing Information has a Boxed Warning for endophthalmitis and reports the incidence rate in patients developing endophthalmitis after receiving the PDS compared with monthly intravitreal ranibizumab. Endophthalmitis cases noted in the Boxed Warning, treatment outcomes, potential contributing factors, and potential mitigations are summarized.
View Article and Find Full Text PDFBackground: Anti-vascular endothelial growth factor (anti-VEGF) agents are widely prescribed for the treatment of neovascular age-related macular degeneration (nAMD). Although studies have investigated patient choice of anti-VEGF agent, little is known regarding factors that influence physician preference of anti-VEGF agent for their patients.
Objective: To describe physician rationale and challenges in prescribing anti-VEGF treatments for patients with nAMD.
Purpose: To evaluate the relationship between retinal fluid location, amount/severity, and vision with ranibizumab-treated neovascular age-related macular degeneration (nAMD).
Methods: In the phase 3 HARBOR trial (NCT00891735), treatment-naive patients with nAMD received ranibizumab 0.5 or 2.
Purpose: To investigate the relationship between retinal fluid and vision in ranibizumab-treated patients with neovascular age-related macular degeneration (nAMD).
Design: Clinical cohort study using post hoc analysis of clinical trial data.
Methods: We assessed data from HARBOR (NCT00891735), a phase III, randomized, controlled trial.
Accuracy of MRI in defining tumor-free margin in optic nerve glioma surgery.
Ophthalmic Plast Reconstr Surg
January 2014
Article Synopsis
- The study aimed to evaluate how effective preoperative MRI is at predicting the histopathologic margin of optic nerve gliomas during surgical removal.
- Researchers analyzed data from 13 patients with diagnosed optic nerve gliomas, comparing MRI findings with what was found during and after surgery.
- Results showed that while MRI identified the tumors correctly, in some cases, the tumors extended beyond what the MRI indicated, affecting surgical planning and outcomes.