One data set, many analysts: Implications for practicing scientists.

Researchers routinely face choices throughout the data analysis process. It is often opaque to readers how these choices are made, how they affect the findings, and whether or not data analysis results are unduly influenced by subjective decisions. This concern is spurring numerous investigations into the variability of data analysis results.

Spatial Bayesian Variable Selection Models on Functional Magnetic Resonance Imaging Time-Series Data.

A common objective of fMRI (functional magnetic resonance imaging) studies is to determine subject-specific areas of increased blood oxygenation level dependent (BOLD) signal contrast in response to a stimulus or task, and hence to infer regional neuronal activity. We posit and investigate a Bayesian approach that incorporates spatial and temporal dependence and allows for the task-related change in the BOLD signal to change dynamically over the scanning session. In this way, our model accounts for potential learning effects in addition to other mechanisms of temporal drift in task-related signals.

Effect of antivenin dose on outcome from crotalid envenomation: 218 dogs (1988-2006).

Objective: To determine whether the dose of antivenin administered is associated with a difference in survival of crotalid-envenomated dogs. A secondary objective was to determine whether other covariables affect survival.

Design: Retrospective study (1988-2006).

Seasonal effects on the aerobic bacterial and fungal conjunctival flora of normal thoroughbred brood mares in Florida.

Objective: To evaluate seasonal effects on the presence or absence of fungal and aerobic bacterial flora of the conjunctival fornix of normal Florida Thoroughbred horses.

Sample Population: Both eyes of 100 horses.

Procedure: Horses with normal anterior segment ophthalmic examinations from three farms in north central Florida were included.

Effects of various diets on gastric tone in the proximal portion of the stomach of horses.

Objective: To assess gastric tone in the proximal portion of the stomach in horses during and after ingestion of 4 diets (2 diets of grain and 2 diets of hay).

Animals: 6 adult horses.

Procedure: A polyester bag with a volume of approximately 1,600 ml was inserted through a gastric cannula into the proximal portion of the stomach of each horse.

Effect of sulfadiazine and pyrimethamine on selected physiologic and performance parameters in athletically conditioned thoroughbred horses during an incremental exercise stress test.

Following the regimen used to treat equine protozoal myeloencephalitis, sulfadiazine (20 mg/kg) and pyrimethamine (1mg/kg) were administered orally once daily to 12 physically conditioned Thoroughbred horses for 4 consecutive days. The horses were randomly assigned to two test groups in a crossover design, with each horse serving as its own control. A stepwise exercise stress test was conducted to exhaustion.

Effect of flunixin meglumine on selected physiologic and performance parameters of athletically conditioned thoroughbred horses subjected to an incremental exercise stress test.

Twelve clinically sound, healthy, athletically conditioned Thoroughbred horses were subjected to an incremental exercise stress test to determine the effects and period of detection of a single dose of flunixin meglumine (1.1 mg/kg by intravenous injection) in serum and urine by ELISA. Flunixin concentrations, performance, and hematologic and clinical chemical parameters were measured.

Supplemental vitamin C appears to slow racing greyhounds.

During strenuous exercise, markers of oxidation increase and antioxidant capacity decreases. Antioxidants such as vitamin C may combat this oxidation stress. The benefits of vitamin C to greyhounds undertaking intense sprint exercise has not been investigated.

Needle core length in sextant biopsy influences prostate cancer detection rate.

Objectives: Prostate cancer detection in biopsies increases with the number of sites and total tissue sampled. Its dependence on needle core fragment length is uncertain.

Methods: We surveyed two consecutive series of sextant needle biopsies from two practices in 1998 to 2000: 251 patients from Pennsylvania (group P) and 1596 from Virginia (group V).