Publications by authors named "Gali Shapira-Zaltsberg"

Article Synopsis
  • Thyroid nodules in children and adolescents are rare but have a higher risk of cancer, prompting this study to assess the Thyroid Imaging Reporting and Data System (TI-RADS) for its effectiveness in predicting malignancy.
  • The study was a multi-institutional retrospective analysis of patients up to 21 years old with thyroid nodules from 2015 to 2020, comparing TI-RADS results with the American Thyroid Association's (ATA) size-based criteria for fine needle aspiration biopsy (FNAB).
  • Results showed that using TI-RADS criteria led to a significant reduction in FNAB recommendations (35.1% vs. 76.6% by ATA guidelines), while achieving high sensitivity in recognizing malignant nodules
View Article and Find Full Text PDF

Background: Thyroid nodules are unusual in children, but when present, they carry a higher risk for malignancy, as compared to adults. Several guidelines have been created to address the risk stratification for malignancy of thyroid nodules in adults, but none has been completely validated in children. A few authors have proposed lowering the size threshold to the American College of Radiology Thyroid Imaging, Reporting and Data System (ACR TI-RADS™) management guidelines to decrease missed carcinomas at presentation in children; however, little information is known regarding their accuracy.

View Article and Find Full Text PDF

To retrospectively correlate imaging findings post-sclerotherapy of low-flow vascular malformations with clinical outcome. We retrospectively evaluated 81 pediatric patients who had sclerotherapy in our department over a 14-year period. Patients with a diagnosis of low-flow vascular malformation, pre and post-treatment ultrasound (US) and clinical follow-up evaluation were included in the study.

View Article and Find Full Text PDF
Article Synopsis
  • Oral contrast does not enhance the ability to accurately diagnose appendicitis in low-weight pediatric patients using CT scans, as no significant difference was found in appendix visualization between those with and without oral contrast.
  • The study involved 100 children aged 2-10 years, comparing outcomes between 37 patients who received oral contrast and 63 who did not.
  • Although overall visualization rates were similar, inter-rater reliability for detecting the appendix was better in the oral contrast group, suggesting further research is needed to clarify the role of oral contrast in appendicitis diagnosis.
View Article and Find Full Text PDF

Background: Surveillance post image-guided percutaneous liver biopsy in children is variable.

Objective: The aim of this study was to assess the value of 4-6-h post-procedure ultrasonography (US) in detecting post-liver-biopsy hemorrhage.

Materials And Methods: This prospective study included pediatric patients who underwent US-guided percutaneous liver biopsies.

View Article and Find Full Text PDF

We describe a case of a 5-day-old male who presented with severe hemoperitoneum due to rupture of one of multiple hepatic hemangiomas, necessitating urgent embolization. Hepatic hemangiomas are common in the pediatric age group. The multifocal type typically presents shortly after birth, and have not been reported to bleed.

View Article and Find Full Text PDF
Article Synopsis
  • - The study aimed to compare two imaging techniques, whole-body diffusion-weighted MRI (WB-DWI-MRI) and FDG-PET/CT, in evaluating and monitoring treatment in children with Hodgkin lymphoma.
  • - Eleven pediatric patients were analyzed using both imaging methods before and after two chemotherapy cycles, with focus on measuring tumor involvement and treatment responses through various metrics.
  • - Results indicated that while WB-DWI-MRI showed some agreement in measurements, it was less effective than FDG-PET/CT for accurate staging and assessing treatment responses in these patients.
View Article and Find Full Text PDF

Infantile hemangiomas are the most frequent vascular soft tissue lumps in the pediatric population. The clinical presentation and evolution of these lesions is characteristic, while the sonographic appearance is classic but not specific. This pictorial essay illustrates the different vascular soft tissue lumps on ultrasound that may mimic infantile hemangiomas.

View Article and Find Full Text PDF

Background: The pediatric reproductive organs are optimally imaged with a full bladder. The filling of the bladder, however, often leads to significant delay in diagnosis and can subject the patient to invasive bladder catheterization. As the key imaging feature in ovarian torsion is unilateral ovarian enlargement, we suspected that a torsed ovary is large enough to be visualized even if the bladder is not well distended.

View Article and Find Full Text PDF
Article Synopsis
  • - The study compares the effectiveness of two ultrasound risk assessment tools for thyroid cancer, the Kwak-TI-RADS and ACR TI-RADS, specifically in children who underwent thyroid ultrasounds.
  • - Results indicate that ACR TI-RADS shows significantly better agreement among radiologists when assessing ultrasound findings compared to the Kwak-TI-RADS, although both tools have similar diagnostic performance for identifying malignancy risk.
  • - The findings suggest that while both methods are reasonably effective for stratifying the risk of thyroid nodules in kids, ACR TI-RADS is the more reliable choice among radiologists.
View Article and Find Full Text PDF

The GTPBP2 gene encodes a guanosine triphosphate (GTP)-binding protein of unknown function. Biallelic loss-of-function variants in the GTPBP2 gene have been previously reported in association with a neuro-ectodermal clinical presentation in six individuals from four unrelated families. Here, we provide detailed descriptions of three additional individuals from two unrelated families in the context of the previous literature.

View Article and Find Full Text PDF

Serine deficiency disorders can result from deficiency in one of three enzymes. Deficiency of the second enzyme, 3-phosphoserine aminotransferase (PSAT), has been reported in two siblings; the eldest investigated for acquired microcephaly, spasticity and epilepsy. Our patient had neurological symptoms at birth.

View Article and Find Full Text PDF

Unlabelled: Previous studies in singleton pregnancies reported conflicting trends in apparent diffusion coefficient (ADC) values with gestational age (GA) and stable relative ADC (rADC; ADC placenta divided by ADC globe) throughout pregnancy. The purpose of our study was to compare the ADC and rADC of placentas of twin and singleton pregnancies.

Materials And Methods: Fetal MRI of 11 twin and 23 singleton pregnancies were retrospectively analyzed.

View Article and Find Full Text PDF

We describe a case of a 14-year-old boy with a history of Legg-Calve-Perthes disease diagnosed at the age of 6 years and development of synovial osteochondromatosis of the same hip joint 7 years later. Synovial osteochondromatosis is very rare in children, and to the best of our knowledge, only a single case of Legg-Calve-Perthes disease and secondary synovial osteochondromatosis was described in the literature in a 35-year-old male, making this the first reported case of Legg-Calve-Perthes disease with development of synovial osteochondromatosis in a pediatric patient.

View Article and Find Full Text PDF