Publications by authors named "Galeote G"

Article Synopsis
  • Bicuspid aortic valve (BAV) is a common congenital heart condition affecting 0.5-2% of the population and is linked to higher incidences in patients with severe aortic stenosis and older adults undergoing surgery.
  • Transcatheter aortic valve replacement (TAVR) is a new treatment option for aortic stenosis, but there's insufficient evidence to identify the best approach for patients with BAV.
  • The report discusses a case of severe acute recoil after TAVR with a self-expanding prosthesis in a patient with heavily calcified BAV and reviews the implications of prosthesis underexpansion in the medium term.
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Transcatheter heart valve embolization is a serious and rare complication of transcatheter aortic valve replacement. Having a strategy for promptly managing transcatheter heart valve embolization is crucial to avoid emergency conversion from transcatheter aortic valve replacement to open-heart surgery. Many cases of transcatheter heart valve embolization occurring with balloon-expandable prostheses such as the SAPIEN 3 (Edwards LifeSciences Corporation) valve and self-expandable prostheses such as the ACURATE neo (Boston Scientific Corporation) valve have been reported in the literature.

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Through these clinical cases, we present a new protocol of action, updated with the latest evidence on percutaneous pulmonary thrombectomy using dedicated catheters, for high-risk PE in pregnant women or during the early postpartum period.

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Article Synopsis
  • Patients with cardiogenic shock (CS) and mitral regurgitation (MR) face high surgical risks, but the study investigates the effectiveness of transcatheter edge-to-edge therapy (TEER) combined with mechanical circulatory support (MCS) for these patients.
  • The MITRA-ASSIST study looked at 24 patients with CS and MR treated with TEER and MCS across nine Spanish centers, revealing a procedural success rate of 95.8% and 87.5% in-hospital survival.
  • At 12 months, 25% of patients died, and 33.3% experienced either death or hospitalization for heart failure, suggesting that TEER combined with MCS could be a viable treatment
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Article Synopsis
  • Covered stents (CS), originally used for coronary perforation, are now being studied for their effectiveness in treating coronary aneurysms (CAA), although data on long-term outcomes is limited.
  • This meta-analysis evaluates major adverse cardiac events (MACE) in patients treated with the new PK Papyrus CS over an average follow-up of 16.2 months, analyzing data from three observational trials.
  • Results show a MACE rate of 14.3%, with higher rates in CAA patients compared to those with coronary perforation, highlighting the need for careful patient selection and treatment optimization for better outcomes.
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Background: High-risk Pulmonary Embolism (PE) mortality remains very high. Systemic thrombolysis is effective but carries significant complications and contraindications related to the hemorrhagic risk. Percutaneous thrombectomy using aspiration catheters may be an alternative in patients with a high bleeding risk.

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The usefulness of drug-eluting balloons (DEBs) has not been fully elucidated in calcified coronary lesions (CCLs). This meta-analysis aimed to evaluate the efficacy of DEBs compared to a drug-eluting stent (DES) in this setting. PubMed, EMBASE and Cochrane were searched through December 2023.

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Background: Previous studies have documented a high rate of implantation success with the ACURATE neo2 valve, as well as a reduction in paravalvular leak (PVL) compared to its predecessor, the ACURATE neo. However, there are no studies that have reviewed and compared the long-term clinical and hemodynamic outcomes of these patients.

Aims: This study aimed to evaluate the results of the ACURATE neo transcatheter aortic valve in a real-world context, and to compare the results of the outcomes of both generations of this device (ACURATE neo and ACURATE neo2), with a specific focus on procedural success, safety, and long-term effectiveness.

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Dynamic road-mapping (DRM) (Dynamic Coronary Roadmap; Philips) offers a real-time, dynamic overlay of the coronary tree on fluoroscopy.

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Objectives: The aim of this study was to analyze the efficacy and safety of percutaneous balloon pericardiotomy (PBP) in oncological patients who present with a malignant pericardial effusion (MPE).

Background: The use of PBP as a treatment for MPE is not standardized due to the limited evidence. Furthermore, the performance of a second PBP for a recurrence after a first procedure is controversial.

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In the 20th century, research focused on cholesterol and lipoproteins as the key mechanism in establishing atherosclerotic cardiovascular disease (ASCVD). Given that some studies demonstrated subclinical atherosclerosis in subjects without conventional cardiovascular risk factors, the elevated low-density lipoprotein (LDL) levels alone cannot account for the entire burden of atherosclerosis. Hence, large-scale clinical trials demonstrated the operation of immune and inflammatory pathways in ASCVD.

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Cardiac computed tomography (CT) scan was performed in a 69-year-old male with atrial fibrillation radiofrequency ablation who was admitted for transcatheter angioplasty of left inferior pulmonary vein (LIPV) stenosis due to recurrent hemoptysis. CT showed complete ostial occlusion in the area of the LIPV. Occlusion of the pulmonary vein ostium is a rare complication.

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There has been suggestion that vitamin D may play a role in protection against severe infection with COVID-19, defined as the need of intensive care unit admission. In this article a potential mechanism involving angiotensin-converting enzyme 2 (ACE2) is proposed.

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An 86-year-old patient with non-valvular atrial fibrillation was referred to our institution to undergo a left atrial appendage (LAA) closure for recurrent gastrointestinal bleeding on direct oral anticoagulants. The transesophageal echocardiogram (TEE) performed the previous day evaluated the morphology and dimensions of the LAA and ruled out any thrombus. During the procedure, a pigtail catheter was inserted into the LAA, observing an unusual image we describe as a culde- sac, without an anomalous connection with any drainage in other vessel or cavity.

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To the best of our knowledge, this case represents the first patient with Mitraclip, Amplatzer, and TricValve devices with a profound clinical improvement and long-term follow-up. In addition, this case illustrates how the treatment of high-risk patients with polyvalvular disease has changed in the last few years.

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Coronary fistulas are not common in patients undergo coronary angiography. It is described, even less frequently, that coronary fistulas may be associated with giant aneurysms along their course. These cases classically are treated surgically.

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