Publications by authors named "Galeev S"
Article Synopsis
- There is a lack of discharge protocols for acute pancreatitis (AP) patients, which the Hungarian Pancreatic Study Group (HPSG) aims to address with a new, validated protocol based on laboratory data and symptoms.
- An international survey revealed that 87.5% of participating medical centers do not have discharge protocols, but those that do see shorter hospital stays and lower readmission rates.
- The HPSG discharge protocol resulted in the lowest average length of hospital stay and demonstrated safety through a low readmission rate, highlighting the need for developing and validating more standardized discharge protocols for AP care.
Article Synopsis
- Acute pancreatitis (AP) is a serious inflammation of the pancreas, and identifying patients at high risk of severe complications early is essential to prevent organ failure and death.
- The study developed a machine learning prediction model called EASY, using data from over 4,700 patients to offer quick assessments of severity through algorithms like XGBoost, achieving an average accuracy of 89.1%.
- The model identifies key risk factors such as respiratory rate, body temperature, and glucose level, and includes a user-friendly web application for easy access to its predictions.
Background: Several anti-cytokine therapies were tested in the randomized trials in hospitalized patients with severe acute respiratory syndrome coronavirus 2 infection (COVID-19). Previously, dexamethasone demonstrated a reduction of case-fatality rate in hospitalized patients with respiratory failure. In this matched control study we compared dexamethasone to a Janus kinase inhibitor, ruxolitinib.
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- The rising incidence of acute pancreatitis (AP) has led to increased medical costs and a concerning 30% mortality rate in severe cases.
- A study involving 2461 patients revealed that hypoalbuminemia (low albumin levels) is common in AP, affecting 19% on admission and 35.7% during hospitalization.
- Severe hypoalbuminemia significantly increases the risk of complications and mortality, with a clear dose-dependent relationship to severity and hospital stay.
Acute pancreatitis (AP) is a life-threatening disease. We aimed to explore the prognostic relevance of renal function based on estimated glomerular filtration rate (eGFR). A prospective registry of AP patients was established by the Hungarian Pancreatic Study Group.
View Article and Find Full Text PDFBackground: Hypertriglyceridemia is the third most common cause of acute pancreatitis (AP). It has been shown that hypertriglyceridemia aggravates the severity and related complications of AP; however, detailed analyses of large cohorts are contradictory. Our aim was to investigate the dose-dependent effect of hypertriglyceridemia on AP.
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- Researchers examined the effectiveness of C-reactive protein (CRP) and white blood cell count (WBC) in assessing acute pancreatitis (AP) through a review of existing studies and data analysis of 1435 patient episodes.
- The study found that CRP levels were not reliable indicators of mortality or severity in AP cases, with low accuracy in predictions regardless of when the levels were measured.
- However, using CRP levels within the first 24 hours after pain onset as a criterion for including patients in clinical trials significantly increased the rates of severe cases and mortality, thus potentially simplifying the patient selection process for trials.
Background: Malignant potential of small (≤20 mm) nonfunctional pancreatic neuroendocrine tumors (sNF-PNET) is difficult to predict and management remain controversial. The aim of this study was to assess the prognosis of sporadic nonmetastatic sNF-PNETs.
Methods: Patients were identified from databases of 16 centers.
Background: Non-functional pancreatic neuroendocrine tumors (NF-PNET) are rare neoplasms being increasingly diagnosed. Surgical treatment or expectant management are both suggested for small NF-PNETs. The aim of this study was to evaluate the outcome of surveillance strategy for small NF-PNETs.
View Article and Find Full Text PDF[Fulminant acute pancreatitis. Are there objective criteria of the disease?].
Vestn Khir Im I I Grek
December 2012
A retrospective analysis has been made of the results of the diagnosis and treatment of 71 patients having severe pancreatitis. As a result, factors were revealed which restrict the possibilities of conservative treatment associated with pessimistic prognosis of the disease. Among them there are pancretitis-specific organic abnormalities (pulmonary, cardio-vascular, renal dysfunctions), diffused pancreonecrosis and infection of destructive zones.
View Article and Find Full Text PDFTo improve surgical outcomes in patients with complicated recurrent, radiation-induced, giant and multiple vesicovaginal fistulas, we have developed a new combined method of fistuloplasty (patent 21350999). The method was used in 12 of 32 operations made in 1997-2007 in the urological clinic of the Kazan Medical University for vesicovaginal fistula in patients aged 19 to 72 years. The technique was applied in women with vesicovaginal fistula located close to the ureteral orifice.
View Article and Find Full Text PDFUnsatisfactory results of surgery in the late course of pancreatic necrosis made us search for indications and variants of operation in the early phase of the disease. As early surgical intervention, the universal approach was used in 7 patients with necrotizing pancreatitis who had a different prevalence of the inflammatory process in the retroperitoneal space. The drainage proved to be effective and enabled us to always prevent generalized infectious complications in the later phases of the disease in absence of local complications specific for open surgery: bleeding and digestive fistulas.
View Article and Find Full Text PDFIn 1988-2003 we operated 156 patients with various ureteral lesions. Of them 7 patients (6 males and 1 female, mean age 34-43 years) received kidney transplant (autotransplantation). Ureteral lesions were caused by previous surgery (n=3), gunshot wound (n=2), urolithiasis (n=2.
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