Exosome-mediated miR-4655-3p contributes to UV radiation-induced bystander effects.

Radiation-induced bystander effects (RIBEs) refer to a series of reactions displaying in nonirradiated cells triggered by signals from irradiated cells. Though bystander effects induced by ionizing radiation have been well studied, there are still limited data on ultraviolet(UV) induced bystander effects(UV-RIBEs). Studies have verified that exosomes, acting as a new tool of intercellular communication, participate in ionizing radiation-induced bystander effect.

Platelet-rich plasma regulating the repair of ultraviolet B-induced acute tissue inflammation: adjusting macrophage polarization through the activin receptor-follistatin system.

Ultraviolet B (UVB) is one of the most common exogenous factors in skin aging, especially photoaging. Once a large amount of UVB accumulates within a short period of time, skin tissue can become inflamed. It has also been found in clinics that platelet-rich plasma (PRP) can promote wound repair; therefore, the aim of this study was to identify the mechanism by which PRP repairs UVB-induced skin photodamage.

Applications and efficacy of platelet-rich plasma in dermatology: A clinical review.

The platelet-rich plasma (PRP) has been studied in bone-related applications for accelerating healing, and the proliferation and regeneration of tissue. Now the dermatological indications increase rapidly in recent years. We have reviewed clinical trials, comparative trials, and meta-analysis of PRP on dermatology through key words and reorganized them into facial rejuvenation, hair, scar, vitiligo, and synergistic effect with fractional CO , with a conclusion that PRP has significant improvements in dermatology.