Rituximab Monotherapy Is Effective in Treating Orbital Necrobiotic Xanthogranuloma.

The authors report a case of a patient with bilateral orbital necrobiotic xanthogranuloma and no associated systemic paraproteinemia. Orbital biopsy showed strong expression of CD20-positive cells. The patient was treated with systemic rituximab monotherapy, with excellent clinical response and marked regression of the orbital lesions on imaging.

Epithelial, non-melanocytic and melanocytic proliferations of the ocular surface.

Ocular surface tumors are commonly encountered by ophthalmologists and ophthalmic pathologists. These tumors have varied clinical manifestations. In this article, we discuss the most commonly encountered non-melanocytic and melanocytic ocular surface tumors, with emphasis on their common clinical features, morphologic patterns, and prognostic factors.

Hyaluronidase: does it take out the sting in vitreoretinal patients?

The purpose of this study was to determine if adding hyaluronidase to the local anesthesia mixture would decrease or eliminate pain during vitreoretinal surgery. Patients having a reoperation of the vitreoretinal space experienced pain after the administration of local anesthesia. A quasi-experimental design, with a convenience sample of 100 repeat patients and a 0-10 visual analog pain scale, was used to test the hypothesis, "Will the addition of hyaluronidase to the local anesthesia mixture decrease or eliminate pain for patients undergoing vitreoretinal surgery multiple times?" The study found that the addition of hyaluronidase did significantly decrease pain for these patients.

Vitreoretinal surgical pain.

The surgical eye nurse found that some patients undergoing vitreoretinal surgery experienced pain after the administration of local anesthesia. This study proposed to determine which local anesthesia technique provides the best comfort level for these patients. A quasi-experimental design, with a convenience sample of 41 patients and a 0-10 visual analog pain scale, was used to test the hypothesis.