Publications by authors named "Gaia Labbate"
Purpose: To explore changes in reticular pseudodrusen (RPD) number and location after the development of macular neovascularization (MNV) in eyes with prior intermediate age-related macular degeneration, focusing on different retinal regions differently affected by MNV.
Methods: This retrospective longitudinal study included intermediate age-related macular degeneration eyes with RPD that developed MNV. Reticular pseudodrusen were assessed at baseline when MNV was diagnosed (MNV stage) and after anti-vascular endothelial growth factor treatment.
Purpose: To assess differences in choriocapillaris (CC) and macular neovascularization (MNV) optical coherence tomography angiography quantitative parameters between long-term persistently nonexudative MNVs (NE-MNVs) and long-term activated NE-MNVs in age-related macular degeneration.
Methods: Age-related macular degeneration patients with treatment-naïve NE-MNVs with >2 years of follow-up and no evidence of exudation within the first 6 months from diagnosis were retrospectively recruited. Two groups were considered according to the occurrence (EX group) or not (NE group) of exudation within the first 2 years of follow-up.
Article Synopsis
- Chronic retinal necrosis is characterized by severe retinal inflammation and has been noted in patients with mild immune issues and conditions like CMV uveitis, often with negative HIV tests.
- Two specific cases are reported involving an 85-year-old woman and a 76-year-old man, both showing symptoms of advanced retinal disease related to long-term necrotizing retinitis.
- Testing revealed no herpesviruses but confirmed the presence of Toxoplasma gondii, suggesting that this organism should be included in the diagnosis for elderly patients with chronic retinal necrosis.
Article Synopsis
- The study focuses on uveitis, a group of inflammatory eye conditions that can threaten vision, and aims to understand its epidemiology and outcomes in Northern Italy.
- A retrospective analysis of 1,105 uveitis patients revealed a predominance of non-infectious cases, with significant rates of conditions like sarcoidosis and herpes-related infections, and noted a majority of female patients around 47 years of age.
- The research highlights notable trends, including rising syphilis cases and the importance of early diagnosis for conditions mimicking uveitis, providing valuable data for clinical practice and understanding of uveitis in the region.
Initial stages of Best vitelliform macular dystrophy (BVMD) and adult vitelliform macular dystrophy (AVMD) harbor similar blue autofluorescence (BAF) and optical coherence tomography (OCT) features. Nevertheless, BVMD is characterized by a worse final stage visual acuity (VA) and an earlier onset of critical VA loss. Currently, differential diagnosis requires an invasive and time-consuming process including genetic testing, electrooculography (EOG), full field electroretinogram (ERG), and visual field testing.
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