Frame-rate adaptive fractionally spaced equalization enabled high-throughput optical camera communication.

Optical camera communication (OCC) has garnered worldwide research attention, due to its immunity to electromagnetic interference (EMI) and efficient utilization of spectrum resources. However, the limited bandwidth of the OCC system and the timing offset of the camera result in low system throughput. To enhance the OCC throughput, we propose and experimentally demonstrate a frame-rate adaptive fractionally spaced equalization algorithm (FA-FSE) for the joint mitigation of severe inter-symbol interference (ISI) and timing offset arising in OCC.

Multiple-signal-joint-processing-based guard interval shortening method for a CS-NFDM system.

Aiming to further improve the spectral efficiency (SE) of a continuous spectrum modulated nonlinear frequency division multiplexing (CS-NFDM) system, we propose a novel ,to the best of our knowledge, multiple-signal-joint-processing (MSJP)-based guard interval (GI) shortening method. In this method, multiple NFDM time-domain signals are jointly processed as a whole to carry out nonlinear Fourier transform and inverse nonlinear Fourier transform (NFT-INFT) operations. These operations can fuse the multiple NFDM time-domain signals together, which is equivalent to the corresponding inverse process of a fiber transmission.

On the multipath interference mitigation for high-speed IM-DD transmissions with Nyquist subcarrier modulation.

The performance of high-speed intensity modulation direct detection (IM-DD) transmissions is severely degraded due to the occurrence of multipath interference (MPI), especially when a higher-order modulation format is utilized. Here, we propose and demonstrate, for the first time to the best of our knowledge, that a Nyquist subcarrier modulation (Nyquist-SCM) format inherently exhibits resistance to the MPI. We experimentally evaluate the MPI tolerance by transmitting 56 Gbit/s PAM-4 signals and Nyquist-SCM 16QAM signals over the 2 km standard single-mode fiber (SSMF) when the C-band semiconductor laser with a linewidth of 1.

Single wavelength MDM-PDM 800-Gb/s net data rate transmission over a standard multimode fiber employing a Kramers-Kronig receiver.

We propose a high-speed multimode fiber short-reach optical interconnect system based on a Kramers-Kronig (KK) field reconstruction with the mode division multiplexing (MDM) and polarization division multiplexing (PDM) technology. In this work, the LP01, LP21a, LP21b, and LP02 modes are selected as independent channels to carry information. The demonstration achieved the 800 Gb/s net data rate per wavelength with a bit-rate-distance-product (BDP) of 8 Tb/s·km.

Experimental demonstration of optical waveform transmission with multiple-eigenvalue 16-APSK modulation.

The multi-eigenvalue multiplexing-based discrete spectrum-modulated nonlinear frequency-division multiplexing (DS-NFDM) system with higher-order modulation format has been demonstrated experimentally. After designing the coefficients of the eigenvalue set and the constellation point distribution of 16-amplitude phase shift keying (16-APSK), the realizations of 14-, 30-, and 46-eigenvalue multiplexed DS-NFDM signals have been implemented. The results show that 46-eigenvalue and 30-eigenvalue multiplexed DS-NFDM signals can transmit 50 km and 400 km over a nonzero dispersion-shifted fiber (NZDSF) under soft-decision forward error correction (SD-FEC) threshold of 2.

Blind frequency offset estimation method based on a minimum phase correction error for a full spectrum modulated NFDM system.

To improve the spectral efficiency of a full spectrum modulated nonlinear frequency division multiplexing (FS-NFDM) system, a blind frequency offset estimation (FOE) method has been proposed. The approach based on the minimum phase correction error can achieve high estimation accuracy of sub-MHz without need of any training symbols. Furthermore, in order to reduce the computational complexity, an eigenvalue-shift method is used to get a coarse search interval of FO, and then the one-dimensional optimization algorithm based on golden section search and parabolic interpolation is used to get the optimal FOE for the coarse search interval.

Pairwise Tomlinson-Harashima precoding for multiple-lane IM-DD transmissions.

As for the photonic interconnection based on the multiple-lane intensity modulation direct detection (IM-DD) transmission, both intra-channel inter-symbol-interference (ISI) originating from bandwidth constraint, and inter-channel performance discrepancy emerging from inter-channel component differences are the major bottleneck for the throughput enhancement. Here, we propose a pairwise Tomlinson-Harshima precoding (P-THP) scheme, in order to simultaneously deal with both intra-channel ISI and inter-channel performance discrepancy. The effective function of the proposed P-THP scheme is experimentally evaluated by transmitting 4-channel 81-GBaud PAM4 signals over 2 km standard single-mode fiber (SSMF).

Mode multicasting without parasitic wavelength conversion.

Optical multicasting, which involves delivering an input signal to multiple different channels simultaneously, is a key function to improve network performance. By exploiting individual spatial modes as independent channels, mode-division-multiplexing (MDM) can solve the capacity crunch of traditional standard single-mode fiber (SSMF) transmission system. In order to realize mode multicasting with high flexibility in future hybrid wavelength-division-multiplexing (WDM) and MDM networks, we propose a mode multicasting scheme without parasitic wavelength conversion, based on the inter-modal four-wave mixing (FWM) arising in the few-mode fiber (FMF).

Transmitter dispersion eye closure quaternary assessment based on linear CNN with 1 × 1 convolutional kernel.

Transmitter dispersion eye closure quaternary (TDECQ) is a vital metric to characterize the quality of four-level pulse amplitude modulation (PAM-4) optical signals. However, the traditional TDECQ assessment scheme is complex and time consuming, with heavy iterative operations. Therefore, accelerating the TDECQ assessment has great significance for photonic data-center interconnection (DCI) applications.

Frequency offset estimation for nonlinear frequency division multiplexing with continuous spectrum modulation.

Carrier frequency offset (CFO) estimation is very important for the optical fiber communications and has been studied widely in linear coherent systems, while only a few works have been reported for nonlinear Fourier transform (NFT) based systems. In continuous spectrum (CS) modulation nonlinear frequency division multiplexing (CS-NFDM) systems, frequency offset (FO) has a great influence on its performance, requiring an improved frequency offset estimation (FOE) method. We found that the oversampling rate R adopted in NFDM to ensure the accuracy of the NFT and inverse NFT (INFT) calculations, would cause the estimation accuracy of the traditional FFT-FOE method to decrease by R times.

Theoretical investigations of weakly- and strongly-coupled multi-core fibers for the applications of optical submarine communications under power and fiber count limits.

The practical cable design for optical submarine communications has a limited fiber pair count due to the mechanical considerations of cable weight and size. Consequently, multi-core fibers (MCFs) could exhibit higher capacity than conventional single-mode fibers (SMFs) thanks to space division multiplexing (SDM). That is because the power supply to a submarine cable is fed by the voltage difference between shores.

C-band 200 Gbit/s/λ PAM-4 transmission over 2-km SSMF using look-up-table pre-distortion combined with nonlinear Tomlinson-Harashima pre-coding.

The performance of high baud-rate intensity modulation direct detection (IM-DD) transmissions is severely degraded by both the linear and nonlinear inter-symbol interference (ISI). Here, we propose and experimentally demonstrate a transmitter-side look-up-table pre-distortion combined with nonlinear Tomlinson-Harashima pre-coding (LUT_PD-NTHP) scheme with the capability of mitigating the linear and nonlinear ISI simultaneously, enabling a C-band 200 Gbit/s/λ PAM-4 transmission over 2-km standard single mode fiber (SSMF), under an end-to-end 10-dB bandwidth of about 20 GHz. The proposed LUT_PD-NTHP scheme is experimentally verified to be superior to the LUT pre-distortion combined with linear THP (LUT_PD-LTHP) scheme, in terms of both the receiver sensitivity and the LUT storage requirement, when only the feed-forward equalization (FFE) is used at the receiver-side.

Joint linear and nonlinear noise monitoring techniques based on spectrum analysis.

As one of the key indicators of signal quality in fiber communication systems, optical signal-to-noise ratio (OSNR) needs to be accurately monitored to ensure reliable network planning, operation, and reconfiguration. OSNR monitoring techniques considering only accumulated amplified spontaneous emission (ASE) noise are no longer suitable for dispersion unmanaged long-haul and dense wavelength division multiplexing (WDM) systems, where the contribution of fiber nonlinearity to total SNR cannot be neglected. In this paper, we propose a modulation-format-transparent, accurate joint linear and nonlinear noise monitoring scheme based on calculation of correlation between two spectral components at the upper and lower sideband of the signal spectrum.

Advancing theoretical understanding and practical performance of signal processing for nonlinear optical communications through machine learning.

In long-haul optical communication systems, compensating nonlinear effects through digital signal processing (DSP) is difficult due to intractable interactions between Kerr nonlinearity, chromatic dispersion (CD) and amplified spontaneous emission (ASE) noise from inline amplifiers. Optimizing the standard digital back propagation (DBP) as a deep neural network (DNN) with interleaving linear and nonlinear operations for fiber nonlinearity compensation was shown to improve transmission performance in idealized simulation environments. Here, we extend such concepts to practical single-channel and polarization division multiplexed wavelength division multiplexed experiments.

Circulating lncRNA SNHG11 as a novel biomarker for early diagnosis and prognosis of colorectal cancer.

Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer mortality worldwide. Emerging evidence indicates that tumour cells release substantial amounts of RNA into the bloodstream, in which RNA strongly resists RNases and is present at sufficient levels for quantitative analyses. Our study aimed to discover blood-based markers for the early detection of CRC and to ascertain their efficiency in discriminating healthy controls, patients with polyps and adenomas and cancer patients.

Circulating lncRNA ABHD11-AS1 serves as a biomarker for early pancreatic cancer diagnosis.

: Recent studies have shown that circulating long noncoding RNAs (lncRNAs) could be stably detectable in the blood of cancer patients and play important roles in the diagnosis of many different cancers. However, the value of lncRNAs in the diagnosis of pancreatic cancer (PC) has not been fully explored. : Eleven PC-related lncRNAs were selected by analyzing bioinformatics databases.

Nonlinear frequency division multiplexing with b-modulation: shifting the energy barrier.

The recently proposed b-modulation method for nonlinear Fourier transform-based fiber-optic transmission offers explicit control over the duration of the generated pulses and therewith solves a longstanding practical problem. The currently used b-modulation however suffers from a fundamental energy barrier. There is a limit to the energy of the pulses, in normalized units, that can be generated.

[In vivo anti-tumor effect and in vitro anti-angiogenic effect of alcohol extract from Euphorbia prostrata].

The study was designed to investigate the anti-tumor and anti-angiogenic effects of alcohol extract from Euphorbia prostrata. The alcohol extract of E. prostrata was prepared, and the tolerated dosage was determined in mice by the test for acute toxicity.

Genotype 4 Hepatitis E Virus Prevalent in Eastern China Shows Diverse Subtypes.

Background: Hepatitis E Virus (HEV), a zoonotic pathogen, uses several species of animal as reservoirs. Swine is considered as the major reservoir for HEV infection in humans. Genotype 4 HEV is the dominant cause of hepatitis E disease in humans in China.

Involvement of the central monoaminergic system in the antidepressant-like effect of catalpol in mice.

Catalpol is a natural iridoid glycoside with diverse bioactivities that is found in abundance in Rehmannia glutinosa Libosch. (Scrophulariaceae). The present study assessed whether catalpol treatment (5, 10, or 20 mg/kg for 14 days by intragastric administration (i.