Publications by authors named "Gage A"

Previous models of depression outcomes have been limited by symptom heterogeneity within populations. This study conducted a retrospective analysis using latent growth mixture models to identify heterogeneous trajectories within a clinical population, subsequently developing machine learning models to predict clinical outcomes based on baseline characteristics and symptom measures. The study analyzed approximately 15,000 clients aged 18-89 in a real-world clinical setting, treated for up to 180-days between 2015 and 2020.

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  • * Mixed CS has become the second most common type of shock in coronary intensive care units, yet there's a lack of high-quality research to inform standard care practices and classifications.
  • * The text proposes a new framework for classifying mixed CS and highlights the need for invasive hemodynamic measures to improve the understanding and management of this condition in clinical settings.
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Dual training in Interventional Cardiology (IC) with other cardiac subspecialties such as Advanced Heart Failure and Transplant Cardiology (AHFTC) and Critical Care Cardiology (CCC) is becoming a pathway for trainees to acquire a needed skill set to deliver comprehensive care for increasingly complex patients in the intensive care unit and catheterization laboratory settings. The makeup of these training pathways varies depending on several factors, with the resultant role of the specialist reflecting this reality. Herein, we review the merits to combined fellowship training for the Interventional Cardiologist, the ideal structure of programs to facilitate this, and how the faculty position for such a unique specialist can enhance a program.

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  • * They focused on adult education fundamentals, necessary training for high-quality patient care, and emphasized diversity, equity, and inclusion.
  • * The resulting paper serves as a guide for trainees, providing insights on the current state of critical care cardiology and outlining future directions for the field’s growth.
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The past decade has seen impressive advances in neuroimaging, moving from qualitative to quantitative outputs. Available techniques now allow for the inference of microscopic changes occurring in white and gray matter, along with alterations in physiology and function. These existing and emerging techniques hold the potential of providing unprecedented capabilities in achieving a diagnosis and predicting outcomes for traumatic brain injury (TBI) and a variety of other neurological diseases.

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  • Acute right ventricular failure (RVF) often occurs in various diseases and can lead to serious health issues, particularly when accompanied by cardiogenic shock (CS).
  • Right-sided temporary mechanical circulatory support (tMCS) devices are utilized to relieve heart stress and improve blood circulation in affected patients, although there is no agreed-upon protocol for their use.
  • This review aims to outline the current treatments for acute RVF, the decision-making process for using tMCS devices, key management elements like fluid levels and anticoagulation, and guidelines for gradually discontinuing tMCS support.
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Unlabelled: Biofilm formation is a common adaptation enabling bacteria to thrive in various environments and withstand external pressures. In the context of host-microbe interactions, biofilms play vital roles in establishing microbiomes associated with animals and plants and are used by opportunistic microbes to facilitate survival within hosts. Investigating biofilm dynamics, composition, and responses to environmental stressors is crucial for understanding microbial community assembly and biofilm regulation in health and disease.

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Background: Although male participation in maternal health has gained increasing recognition and support over the years, little is known about male involvement during pregnancy in the Democratic Republic of the Congo. This paper identified male involvement patterns during pregnancy and evaluated their associations with pregnancy and birth preparedness knowledge, gender-equitable attitudes, self-efficacy, and co-parental relationship factors. Lastly, it explored the moderating effect of gender-equitable attitudes and intimate partner violence on the association between relationship satisfaction and male involvement.

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Background: Child marriage has been associated with a range of negative maternal and reproductive health outcomes. This study explored these associations in Liberia and Sierra Leone and examined how child marriage intersected with other measures of social disadvantage.

Methods: Data were derived from 631 and 1,325 married or cohabitating women aged 20-24 interviewed in the 2019-2020 Liberia and 2019 Sierra Leone Demographic and Health Surveys, respectively.

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Pericardiocentesis is an important diagnostic and therapeutic procedure. In the setting of cardiac tamponade, pericardiocentesis can rapidly improve hemodynamics, and in cases of diagnostic uncertainty, pericardiocentesis allows for fluid analysis to aid in diagnosis. In contemporary practice, the widespread availability of ultrasonography has made echocardiographic guidance the standard of care.

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This study evaluated the effect of Momentum-an integrated family planning, maternal and newborn health, and nutrition intervention-on postpartum family planning norms and behaviors among ever married and never-married first-time mothers age 15-24 in Kinshasa, Democratic Republic of the Congo. Using data collected in 2018 and 2020, we conducted an intent-to-treat analysis among 1,927 first-time mothers who were about six-months pregnant at enrollment. Difference-in-differences models were run for panel data and treatment effects models with inverse-probability weighting for endline-only outcomes.

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  • Cardiogenic shock remains a critical health issue with high mortality rates, and no significant new treatments have emerged in decades, making management difficult.
  • A collaborative, multidisciplinary approach involving specialized "shock teams" is being promoted to improve patient outcomes in high-volume clinical settings.
  • The proposal aims to establish a Cardiogenic Shock Team Collaborative to enhance care protocols, education, and overall performance, similar to successful initiatives in other medical areas.
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Introduction: The prognosis of metastatic non-small cell lung cancer (NSCLC) has been improved by the use of immune checkpoint inhibitors (ICI). Unfortunately, in some cases, cancer cells will develop resistance mechanisms. In case of progression in a limited number of lesions (oligoprogression), focal treatment with radiotherapy is proposed while continuing the ICI therapy.

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Background: Over the past decade there has been increasing interest in critical care medicine (CCM) training for cardiovascular medicine (CV) physicians either in isolation (separate programs in either order [CV/CCM], integrated critical care cardiology [CCC] training) or hybrid training with interventional cardiology (IC)/heart failure/transplant (HF) with targeted CCC training.

Objective: To review the contemporary landscape of CV/CCM, CCC, and hybrid training.

Methods: We reviewed the literature from 2000-2022 for publications discussing training in any combination of internal medicine CV/CCM, CCC, and hybrid training.

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Introduction And Methods: This study sought to determine the prevalence and predictors of modern contraceptive use among non-refugee and refugee Somali women in Nairobi City, Kenya. The analysis was based on 976 currently married Somali women aged 15-39 years (non-refugees; 523, refugees; 415) who were interviewed in a 2021 household survey conducted in Kamukunji, Embakasi, and Ruaraka sub-counties of Nairobi City. The analysis was stratified by refugee status and multivariable logistic regression were run to determine predictors of modern contraceptive use in each group.

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Over the last three years, research has focused on examining cardiac issues arising from coronavirus disease 2019 (COVID-19) infection, including the emergence of new-onset atrial fibrillation (NOAF). Still, no clinical study was conducted on the persistence of this arrhythmia after COVID-19 recovery. Our objective was to compose a narrative review that investigates COVID-19-associated NOAF, emphasizing the evolving pathophysiological mechanisms akin to those suggested for sustaining AF.

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Background: The COVID-19 pandemic disrupted health systems in 2020, but it is unclear how financial hardship due to out-of-pocket (OOP) health-care costs was affected. We analysed catastrophic health expenditure (CHE) in 2020 in five countries with available household expenditure data: Belarus, Mexico, Peru, Russia, and Viet Nam. In Mexico and Peru, we also conducted an analysis of drivers of change in CHE in 2020 using publicly available data.

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  • The study aimed to create an animal model that distinguishes between joint instability and inflammation's effects on posttraumatic osteoarthritis (PTOA), proposing that their modified drilling procedure would induce cartilage damage and inflammation without altering gait.
  • Twenty-four Yucatan minipigs were divided into two groups, one undergoing the modified intra-articular drilling (mIAD) and the other serving as a sham control, with outcomes assessed through various evaluations 15 weeks post-surgery.
  • Results showed that mIAD knees had significantly more cartilage damage and inflammation markers than controls, but no notable changes in gait mechanics, suggesting this model is useful for studying inflammatory roles in PTOA and developing relevant therapies.
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More than 16 million Americans provide unpaid care for someone with Alzheimer's disease and related dementias (ADRD). During the COVID-19 pandemic, unpaid caregivers experienced increased chronic severe stress from widespread closures and social distancing. We conducted eight surveys from March 2020 to March 2021 among a cohort of over 10,000 individuals.

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Objectives: This article presents the effect of Momentum, a nursing student-led community-based service delivery project, on postpartum family planning (FP) outcomes among first-time mothers in Kinshasa, Democratic Republic of the Congo.

Study Design: We employed a quasi-experimental design, with three intervention and three comparison health zones (HZ). Data were collected through interviewer-administered questionnaires in 2018 and 2020.

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Background: During the COVID-19 pandemic, governments and researchers have used routine health data to estimate potential declines in the delivery and uptake of essential health services. This research relies on the data being high quality and, crucially, on the data quality not changing because of the pandemic. In this paper, we investigated those assumptions and assessed data quality before and during COVID-19.

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The spread of COVID-19 and associated deaths have remained low in Ethiopia. However, the pandemic could pose a public health crisis indirectly through disruptions in essential health services. The aim of this study was to examine disruptions in health service utilization during the first nine months of the COVID-19 pandemic across 10 regions in Ethiopia.

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Introduction: Evidence shows that an expanded range of contraceptive methods, client-centered comprehensive counseling, and voluntary informed choice are key components of successful family planning programs. This study assessed the effect of the Momentum project on contraceptive choice among first-time mothers (FTMs) age 15-24 who were six-months pregnant at baseline in Kinshasa, Democratic Republic of the Congo, and socioeconomic determinants of the use of long-acting reversible contraception (LARC).

Methods: The study employed a quasi-experimental design, with three intervention health zones and three comparison health zones.

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