Publications by authors named "Gagandeep Sooch"

Article Synopsis
  • Capsaicin is a compound found in chili peppers and has been consumed for thousands of years, recognized for its nutritional benefits and various health properties.
  • Capsaicin activates the TRPV1 channel, having both beneficial effects like vasodilation and harmful effects like vasoconstriction, particularly for those with inflammatory conditions.
  • The review highlights how capsaicin’s effects can vary based on inflammation levels, emphasizing the risk of adverse outcomes like vasospasm and myocardial infarction when consumed excessively.
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This 2020 Special Issue "TRPC channels" of was dedicated to commemorating the 25th anniversary of discovery of the Transient Receptor Potential Canonical (TRPC) channel subfamily [...

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Twenty-five years ago, the first mammalian Transient Receptor Potential Canonical (TRPC) channel was cloned, opening the vast horizon of the TRPC field. Today, we know that there are seven TRPC channels (TRPC1-7). TRPCs exhibit the highest protein sequence similarity to the TRP channels.

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