Publications by authors named "Gaetano Panese"

Article Synopsis
  • - HPV is a significant global health issue, primarily affecting women by increasing the risk of cervical cancer, with current treatments limited mainly to surgery and topical solutions.
  • - A study involving 163 women with HPV infections tested a combination of natural therapies—EGCG, folic acid, vitamin B12, and hyaluronic acid—over three months to assess their effectiveness.
  • - Results showed that the treatment group had a notable decrease in HPV positivity and improvement in cervical lesions compared to the control group after three and six months.
View Article and Find Full Text PDF
Article Synopsis
  • Pelvic floor stability is affected by various biomechanical, anatomical, and physiological factors, crucial for treating conditions like pelvic organ prolapse (POP).
  • The review identifies the uterosacral ligament's strength as vital for pelvic support and explores both non-surgical treatments, like vitamin C supplementation, and innovative surgical techniques to enhance treatment outcomes.
  • The conclusions emphasize a multifaceted approach to treatment that integrates different factors affecting pelvic floor integrity, suggesting personalized strategies could improve outcomes for patients.
View Article and Find Full Text PDF

Despite their general good health, an increasing proportion of elderly individuals require surgery due to an increase in average lifespan. However, because of their increased vulnerability, these patients need to be handled carefully to make sure that surgery does not cause more harm than good. Age-related postoperative cognitive disorders (POCD) and postoperative delirium (POD), two serious consequences that are marked by adverse neuropsychologic alterations after surgery, are particularly dangerous for the elderly.

View Article and Find Full Text PDF
Article Synopsis
  • This study investigated the effects of a 3-month treatment regimen of EGCG, vitamin D, and D-chiro-inositol on surgical outcomes for women with uterine fibroids undergoing laparoscopic myomectomy.
  • Results showed that women who received the treatment had shorter surgery times and less blood loss compared to those in the control group.
  • The treatment was found to be safe, with no negative effects on liver function, suggesting it could be a beneficial option for women with uterine fibroids.
View Article and Find Full Text PDF
Article Synopsis
  • - The authors evaluated the risks and outcomes associated with uterine fibroid morcellation, specifically the potential spread of hidden uterine leiomyosarcoma (LMS) during laparoscopic versus open myomectomies, considering the influence of adherence to medical guidelines.
  • - They conducted a comprehensive review of literature from 1990-2021, concluding that while there is a general risk for LMS post-myomectomy, proper adherence to scientific guidelines can minimize risks associated with laparoscopic procedures.
  • - The review emphasizes that gynecological societies do not outright ban morcellation but recommend it based on individual patient assessments, urging doctors to provide thorough information to patients during the consent process.
View Article and Find Full Text PDF

Objectives: The aim of this study was to evaluate intrauterine adhesion formation after laparoscopic and laparotomic myomectomy.

Design: This is a prospective, multicenter, observational study (ClinicalTrials.gov ID: NCT04030273).

View Article and Find Full Text PDF

Objective: On May 13, 2020, the Italian government Pharmaceutical Agency (AIFA) stopped ulipristal acetate (UPA) treatments for uterine fibroids (UFs), so patients shifted to other natural treatments. The authors tested the patients' compliance with UF natural treatments.

Methods: Thirty patients of reproductive age (30-45 years) affected by UFs stopped UPA intake and started epigallocatechin gallate (EGCG) plus vitamin D3 treatment.

View Article and Find Full Text PDF