Publications by authors named "Gaetano Liberti"
Two patients with CSF shunting systems exhibited symptoms of altered intracranial pressure. Initial neuroimaging led to misinterpretation, but integrating clinical history and follow-up imaging revealed the true diagnosis. In the first case, reduced ventricular size was mistaken for CSF overdrainage, while the actual problem was increased intracranial pressure, as seen in slit ventricle syndrome.
View Article and Find Full Text PDFBackground Odontoid C2 fractures account for 9% to 15% of adult cervical spine fractures. The aim of this study is to report the incidence of a previous described Y-shaped trabecular bone structure (TBS) in the odontoid process in a larger sample of patients who performed a CT cervical scan following a cervical trauma to investigate if its absence can increase the risk of the odontoid process fracture of the axis. Methods A retrospective review of 245 patients who performed a CT cervical scan in our University Hospital, as results of cervical spine injury, was performed during a 12-month period between May 2020 and May 2021.
View Article and Find Full Text PDFArticle Synopsis
- Glioblastoma (GB) is a deadly brain cancer with limited treatment options and a median survival of only 12-15 months, prompting the need for improved therapeutic screening methods.
- This study introduced a functional precision medicine approach utilizing organoids from resected GB tumors, combined with metabolic imaging to assess quick responses to anticancer treatments, validating the method with temozolomide (TMZ).
- Results indicated successful differentiation between TMZ responders and non-responders within a week post-surgery, uncovering new target genes related to treatment responses and a 17-gene signature linked to patient survival, highlighting the potential to refine current biomarkers.
. Systemic immunity and inflammation indexes (SI) derived from blood cells have gained increasing attention in clinical oncology as potential biomarkers that are associated with survival. .
View Article and Find Full Text PDFObjective: We describe a severe case of vaccine-induced immune thrombotic thrombocytopenia (VITT) after the first dose of the ChAdOx1 nCoV-19 vaccine leading to massive ischemic stroke.
Methods: A 42-year-old woman developed acute left hemiparesis (NIHSS 12) 9 days after the first vaccine dose.
Results: The blood tests revealed low platelets (70 10/μL) and severe increment of D-dimer (70,745 ng/mL FEU).