Intravitreal ranibizumab for predominantly hemorrhagic choroidal neovascularization in age-related macular degeneration.

Purpose: To evaluate the effects of intravitreal ranibizumab monotherapy on predominantly hemorrhagic choroidal neovascularization with foveal involvement associated with age-related macular degeneration.

Materials And Methods: Twenty-two consecutive eyes with hemorrhagic neovascularization were treated with 3 monthly intravitreal ranibizumab injections. Additional injections were administered according to retreatment criteria during 12 months of follow-up.

Macular pucker: to peel or not to peel the internal limiting membrane? A microperimetric response.

Background: To compare functional and anatomical outcomes after idiopathic macular pucker removal between eyes that underwent internal limiting membrane (ILM) peeling and eyes that did not.

Methods: In this multicentric, randomized clinical trial, 60 eyes of 60 patients affected with idiopathic macular pucker were enrolled. Thirty eyes underwent 23-gauge pars plana vitrectomy associated with ILM peeling ("ILM peeling group"), whereas 30 eyes did not undergo ILM peeling ("ILM not peeling group").

Theoretical model and design of a device to reduce the influence of environmental factors on refractive surgery outcomes.

Recently many different groups show that environmental temperature and relative humidity affects the outcomes of refractive surgery performed by excimer lasers in an unpredictable fashion. A theoretical model of the water vapor absorption at 193 nm wavelength is presented and discussed in order to quantitatively assess the influence of environmental parameters on the laser energy that actually reaches the corneal surface. Model simulations show that laser energy absorption (up to 7% of the available energy) occurs along the path of laser beam, into the existent space between the laser beam source and the patient's eye, and is caused by environmental temperature and relative humidity (respectively 35 degrees C and 95%).