Discharge of biocidal products from healthcare activities into a sewage system-a case study at a French university hospital.

This study focused on the presence of three biocidal products specific to healthcare facilities, i.e. chlorhexidine digluconate (CHD), bis(aminopropyl)laurylamine (BAPLA), and didecyldimethylammonium chloride (DDAC), in a hospital sewage system.

Comparative assessment of local tolerance of alcohols commonly used in alcohol-based hand rubs for hand hygiene.

Hand hygiene plays a key role in nosocomial infection prevention. To achieve users' adherence, products' dermal tolerance is essential. We aimed at making a comparative assessment of skin irritation and phototoxicity of the 3 alcohols commonly used in alcohol-based hand rubs (Ethanol, Propan-2-ol, Propan-1-ol) at 60, 70, 80 or 85% w/w in water or with co-formulates (hydrating, emollient and skin protective agents).

Aqueous mixtures of di-n-decyldimethylammonium chloride/polyoxyethylene alkyl ether: dramatic influence of tail/tail and head/head interactions on co-micellization and biocidal activity.

Mixed aggregate formation and synergistic interactions of binary surfactant mixtures of di-n-decyldimethylammonium chloride, [DiC(10)][Cl], with polyoxyethylene alkyl ethers, C(i)E(j) (i=10, 12, j=4, 6, 8), have been investigated for various [DiC(10)][Cl]/C(i)E(j) ratios. The critical aggregation concentration of the binary mixtures has been determined by tensiometry, and the aggregate characteristics (i.e.

Structure-activity relationship of cyclodextrin/biocidal double-tailed ammonium surfactant host-guest complexes: towards a delivery molecular mechanism?

In aqueous solution, the biocidal double-tailed cationic surfactant, di-n-decyl-dimethyl-ammonium chloride can form inclusion complexes with various cyclodextrins (alpha-CD, beta-CD, gamma-CD, HP-alpha-CD, HP-beta-CD and CM-beta-CD). A physicochemical study has been performed to investigate the association parameters of these host-guest complexes by combining the use of ammonium and chloride selective electrodes, NMR spectroscopy and molecular modeling. stoichiometries, equilibrium constants and geometries were determined by resorting to a specific algorithm.