Comparison of Kidney Graft Function and Survival in an Emulated Trial With Living Donors and Brain-Dead Donors.

Living donation (LD) transplantation is the preferred treatment for kidney failure as compared to donation after brain death (DBD), but age may play a role. We compared the 1-year estimated glomerular filtration rate (eGFR) after kidney transplantation for recipients of LD and DBD stratified by recipient and donor age between 2015 and 2018 in a matched cohort. The strength of the association between donation type and 1-year eGFR differed by recipient age ( < 0.

Procurement of Uterus in a Deceased Donor Multi-Organ Donation National Program in France: A Scarce Resource for Uterus Transplantation?

Uterus transplantation is a new possibility for women suffering from absolute uterine infertility to become pregnant and have children. In the case of a deceased donor, a list of exclusion criteria is defined to ensure the high quality of the uterus graft. This study evaluates the number of potentially available uterus grafts based on the pre-defined exclusion criteria in a national deceased donor multi-organ donation program in France.

Critical pathways for controlled donation after circulatory death in France.

Introduction: In 2015, France authorised controlled donation after circulatory death (cDCD) according to a nationally approved protocol. The aim of this study is to provide an overview from the perspective of critical care specialists of cDCD. The primary objective is to assess how the organ donation procedure affects the withdrawal of life-sustaining therapies (WLST) process.

Effect of Lung-Protective Ventilation in Organ Donors on Lung Procurement and Recipient Survival.

Previous studies have shown that a lung-protective strategy, which aims at minimizing ventilator-induced lung injury (with low Vt/high positive end-expiratory pressure as the main pillars), in selected potential organ donors after brain death increased lung eligibility and procurement. This prospective nationwide cohort study aimed to evaluate the impact of lung-protective ventilation (PV) in nonselected donors on lung procurement and recipient survival after lung transplantation. We included all reported donors aged 18-70 years after brain death without a lung recovery contraindication and with at least one organ recovered between January 2016 and December 2017.

Continuous Monitoring of Transplant Center Performance: Different Options for Different Goals.

Background: In France, the need for continuous monitoring of transplant center performance has recently become apparent. Cumulative sum (CUSUM) monitoring of transplantation is already been used to monitor transplant outcomes in the United Kingdom and in the United States. Because CUSUM monitoring can be applied by different methods, the objective was to assess and compare the performance of different CUSUM methods for detecting higher than expected (ie, excessive) graft failure rates.

CONSTANCES: a general prospective population-based cohort for occupational and environmental epidemiology: cohort profile.

Unlabelled: WHY THE COHORT WAS SET UP?: CONSTANCES is a general-purpose cohort with a focus on occupational and environmental factors.

Cohort Participants: CONSTANCES was designed as a randomly selected sample of French adults aged 18-69 years at inception; 200 000 participants will be included.

Data Collection Phases: At enrolment, the participants are invited to complete questionnaires and to attend a health screening centre (HSC) for a health examination.

Seven out of 10 couples treated by IVF achieve parenthood following either treatment, natural conception or adoption.

The aim of this study was to explore the achievement of parenthood 8 years after starting IVF, considering multiple pathways to parenthood during and after IVF treatment. Medical data on 6507 couples who began IVF between 2000 and 2002 were obtained from the databases of eight French IVF centres. Information on long-term outcome was available for participants in the 2008-2010 postal survey.

In an occupational health surveillance study, auxiliary data from administrative health and occupational databases effectively corrected for nonresponse.

Objectives: To show how reweighting can correct for unit nonresponse bias in an occupational health surveillance survey by using data from administrative databases in addition to classic sociodemographic data.

Study Design And Setting: In 2010, about 10,000 workers covered by a French health insurance fund were randomly selected and were sent a postal questionnaire. Simultaneously, auxiliary data from routine health insurance and occupational databases were collected for all these workers.

Psychosocial exposures at work and mental health: potential utility of a job-exposure matrix.

Objective: To examine the associations between psychosocial exposures at work and depressive symptoms by using two independent French national databases.

Methods: A job-exposure matrix of psychosocial work exposures was constructed from data collected by the national medical monitoring of occupational risks survey in 2003. Depressive symptoms came from the 2002 to 2003 decennial health survey.

Working conditions and depressive symptoms in the 2003 decennial health survey: the role of the occupational category.

Introduction: The aim of this study is to describe the associations between depressive symptoms and some working conditions according to broad occupational categories in France.

Methods: These data came from the decennial health survey conducted in 2003 in France by the National Institute for Statistics and Economics Studies (6,082 men, 5,521 women). The data collected included: depressive symptoms (Center for Epidemiological Studies-Depression Scale), psychosocial factors at work and potential confounding factors.

Depressive symptoms and atypical jobs in France, from the 2003 Decennial health survey.

Background: The objective is to study the relations between depressive symptoms and atypical jobs in the working population in France and to determine if these associations might be linked with psychosocial and organizational constraints.

Methods: The data come from the 2003 Decennial health survey and concern 11,895 workers. Depressive symptoms were measured by the CES-D scale.

[The use of national public health surveys in the general population for the surveillance of occupational risks].

The primary mission of the Department of Occupational Health of the French Institute for Public Health Surveillance (InVS) is to monitor health in relationship to occupational activities. Data produced in other fields can contribute to its mission in particular data from public health surveys carried out among the general population in France. A study on occupational and mental health using data from the 2002-2003 Insee Decennial Health Survey serves as an exemplary case to illustrate this process.

Deterioration of quality of life of high-risk breast cancer patients treated with high-dose chemotherapy: the PEGASE 01 Quality of Life Study.

Objective: The aim of this study was to compare the quality of life (QOL) of high-risk breast cancer patients included in a randomized clinical trial (PEGASE 01) comparing conventional chemotherapy versus adding an additional high-dose chemotherapy (HDC) cycle with blood stem cell support.

Methods: A total of 314 patients were included in the clinical trial. QOL evaluations were available for 199 patients.

Cross-cultural validation of the Decisional Conflict Scale in a sample of French patients.

Introduction: The Decisional Conflict Scale (DCS, 16 items, 5 dimensions) designed to measure the level of decisional conflict experienced by patients making health care decisions has not yet been validated in French.

Methods: A national sample of French cancer patients (n=644) facing the decision to undergo BRCA genetic testing was tested for this purpose, including a control group and an experimental group who had received an information booklet. Reliability and criterion validity were investigated.