Early central blood pressure elevation in adult patients with 21-hydroxylase deficiency.

Context: Controversial data exist on cardiovascular damages in patients with congenital adrenal hyperplasia (CAH).

Objective: To assess blood pressure and early cardiovascular damages on a large cohort of adult CAH patients and control individuals.

Design: Case-control study.

Polyendocrinopathy Resulting From Pembrolizumab in a Patient With a Malignant Melanoma.

Introduction: Checkpoint inhibitors have significantly improved the prognosis of patients with advanced melanoma. These cancer immunotherapy drugs have specific endocrine autoimmune toxicity. We describe a case of an adrenal insufficiency secondary to pembrolizumab, an anti-programmed cell death-1 monoclonal antibody.

Influence of diagnostic criteria on the interpretation of adrenal vein sampling.

Guidelines promote the use of adrenal vein sampling (AVS) to document lateralized aldosterone hypersecretion in primary aldosteronism. However, there are large discrepancies between institutions in the criteria used to interpret its results. This study evaluates the consequences of these differences on the classification and management of patients.