Publications by authors named "Gaelle Borredon"
Article Synopsis
- Diagnosing infectious diseases is complicated, and this study aimed to analyze diagnostic uncertainty (DU) in patients with positive blood cultures (PBC) and assess how it affects antibiotic treatment and patient outcomes.
- The research involved real-time communication of PBC results to infectious disease specialists, who reviewed patient charts and provided treatment advice, highlighting that 47% of cases experienced diagnostic uncertainty.
- Findings indicated that DU was linked to higher hospitalization rates, increased use of broad-spectrum antibiotics, and a greater likelihood of poor outcomes, including death during hospitalization.
Objectives: We studied the impact of simplified therapeutic guidelines (STGs) associated with accompanied self-antibiotic reassessment (ASAR) on antibiotic use.
Methods: Prospective antibiotic audits and feedback took place at 15 hospitals for 12 months, allowing STGs with ≤15 drugs to be devised. STGs were explained to prescribers through sessions referred to as ASAR.