State of the art review: coronary artery disease in patients with inflammatory bowel disease: mechanisms, prevalence, and outcomes.

Extraintestinal disease manifestations of inflammatory bowel disease (IBD), such as arthritis and uveitis, have been well described in the medical literature. However, there has been growing evidence suggesting an association between IBD and both coronary artery disease (CAD) and acute myocardial infarctions (AMI). In this critical review, the pathogenesis of proatherogenic inflammatory markers (CD40-CD40L, IL-6, and TNF-α) are summarised along with clinical evidence that supports the association of these makers with CAD.

Crystal structure of 1,3-bis-(2,3-di-methyl-quinoxalin-6-yl)benzene.

The title compound, C26H22N4 (I), was synthesized by C-H iridium-catalyzed borylation followed by Suzuki coupling. The mol-ecular structure of (I) consists of a central benzene ring with 3-di-methyl-quinoxalin-6-yl groups at the 1 and 3 positions. These 2,3-di-methyl-quinoxalin-6-yl groups twist significantly out of the plane of the benzene ring.