Factors associated with cardiac implantable electronic device-related infections, New South Wales, 2016-21: a retrospective cohort study.

Objectives: To quantify the rate of cardiac implantable electronic device (CIED)-related infections and to identify risk factors for such infections.

Design: Retrospective cohort study; analysis of linked hospital admissions and mortality data.

Setting, Participants: All adults who underwent CIED procedures in New South Wales between 1 January 2016 and 30 June 2021 (public hospitals) or 30 June 2020 (private hospitals).

Real-world evidence on the association between cardiac implantable electronic device infection and all-cause mortality.

Aims: An infection following cardiac implantable electronic device (CIED) procedure is a serious complication, but its association with all-cause mortality is inconsistent across observational studies. To quantify the association between CIED infection and all-cause mortality in a large, contemporary cohort from New South Wales, Australia.

Methods And Results: This retrospective cohort study used linked hospital and mortality data and included all patients aged >18 years who underwent a CIED procedure between July 2017 and September 2022.