Publications by authors named "Gabriella Siciliano"
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Synopsis of recent research by authors named "Gabriella Siciliano"
- Gabriella Siciliano's research extensively investigates the role of extracellular microfibrils, particularly fibrillin-1 and fibrillin-2, in bone health and disease, revealing their differential effects on TGF-β and BMP bioavailability during bone formation.
- Her studies demonstrate that mutations in fibrillin lead to skeletal manifestations in conditions such as Marfan syndrome, with findings indicating impaired osteoblast function and enhanced osteoclastogenesis linked to altered TGF-β signaling pathways.
- In addition to bone biology, Siciliano explores the mechanisms of alternative splicing and gene regulation, contributing to understanding mRNA processing and its implications in gene expression control, exemplified by her work on the rpL3 gene and Drosophila oogenesis.
