Publications by authors named "Gabriella C Speakman"
SATB2 expression in oral sarcomatoid (spindle cell) squamous cell carcinoma: clinicopathologic and immunophenotypic characterization of 10 cases.
Oral Surg Oral Med Oral Pathol Oral Radiol
January 2025
Article Synopsis
- The study investigates 10 cases of sarcomatoid squamous cell carcinoma (sSCC), a rare type of oral cancer, examining their clinicopathologic and immunophenotypic characteristics, particularly looking at SATB2 expression.
- These cases, collected from 2000 to 2023, primarily affected older adults with a male-to-female ratio of 1.5:1, most commonly occurring in the tongue, and showed a variety of tumor appearances and microscopic features.
- Results indicated that while all lesions tested positive for certain markers, SATB2 expression can vary significantly and may lead to misdiagnosis, highlighting the importance of using multiple markers for accurate identification of oral s